GENERIC NAME: telaprevir
BRAND NAME: Incivek (This drug was discontinued by the manufacturer, but will be available until October 2014)
DRUG CLASS AND MECHANISM: Telaprevir is a man-made antiviral medication that targets hepatitis C virus (HCV). Similar drugs include simeprevir (Olysio) and boceprevir (Victrelis). These drugs are called direct-acting antiviral agents because they act directly on hepatitis C virus. They block the replication of hepatitis C virus in human cells by binding to and inhibiting protease enzymes that HCV use for reproducing. Inhibiting viral replication reduces HCV viral load in the body to undetectable levels in some patients. The FDA approved Telaprevir in August 2011.
GENERIC AVAILABLE: No
PREPARATIONS: Tablets: 375 mg
STORAGE: Store telaprevir tablets between temperatures of 15 C 30 C (59 F 86 F).
PRESCRIBED FOR: Telaprevir is used for treating chronic hepatitis C genotype 1 infection, in combination with peginterferon alfa (PegIntron) and ribavirin (Rebetol) in adults with compensated liver disease who have not been treated before or failed previous treatment.
Adults (18 years of age and older): The recommended dose of telaprevir (is three 375 mg tablets (1125 mg) by mouth twice daily given 10 to 14 hours apart with food that is not low in fat. Fat increases the absorption of telaprevir.
Quick GuideHepatitis C Pictures Slideshow: Transmission, Symptoms and Treatment
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