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TEGASEROD-ORAL, Zelnorm (cont.)

HOW TO USE: Take this medication by mouth, usually twice daily before meals; or as directed by your doctor. Take this medication for 4 to 6 weeks. If you symptoms improve, your doctor may recommend a second 4 to 6 weeks of treatment.

SIDE EFFECTS: Headache or joint pain may occur. If any of these effects persist or worsen, notify your doctor promptly. If diarrhea occurs, it may be only temporary during the first week of treatment. If it occurs, your doctor may recommend that you drink plenty of liquids to avoid becoming dehydrated. If the diarrhea does not resolve on its own after 2 days or if you feel very weak, have severe cramping, dizziness/lightheadedness/fainting, or irregular heartbeats, stop tegaserod and tell your doctor immediately. If you experience different or suddenly worsening stomach/abdominal pain compared to your regular IBS symptoms, with or without bloody stools, stop taking this medication and tell your doctor immediately. This could be a sign of a rare but serious intestinal problem (ischemic colitis). An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: This medication is not recommended for use if you have the following medical conditions: severe kidney disease, moderate to severe liver disease, a history of certain stomach disorders (e.g., bowel obstruction, symptomatic gallbladder disease, suspected sphincter of Oddi dysfunction, or abdominal adhesions). Tell your doctor your medical history, especially of: current or repeat episodes of diarrhea or stomach/abdominal pain, and of any allergies you may have. Tell your doctor if you are pregnant before using this medication. Tegaserod should be used during pregnancy only if clearly needed. It is not known whether this drug passes into breast milk. Breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.



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