tamsulosin, Flomax (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC AVAILABLE: Yes
PREPARATIONS: Capsules: 0.4mg.
STORAGE: Capsules should be stored at room temperature, 15-30 C (59-86 F).
PRESCRIBED FOR: Tamsulosin is used to treat men who are having problems urinating because of BPH. Tamsulosin is not approved for the treatment of high blood pressure.
DOSING: The recommended dose is 0.4 or 0.8 mg once daily about 30 minutes after the same meal time each day. When taken on an empty stomach, more of the medication is absorbed. This could cause a greater effect and potentially a drop in blood pressure.
DRUG INTERACTIONS: The elimination of tamsulosin from the body may be reduced by erythromycin, ketoconazole (Nizoral, Extina, Xolegel, Kuric), paroxetine (Paxil), cimetidine (Tagamet), ritonavir (Norvir), lopinavir, and other drugs that reduce the elimination of drugs by liver enzymes. Reduced elimination may lead to increased side effects of tamsulosin. PDE-5 inhibitors (for example, vardenafil [Levitra, Staxyn], Adcirca, sildenafil [Viagra, Revatio], tadalafil [Cialis]) add to the blood pressure lowering effects of tamsulosin and may result in severe blood pressure reduction.
PREGNANCY: Tamsulosin is not prescribed for women.
NURSING MOTHERS: This medication is used only in men. It is not known if tamsulosin is secreted into breast milk.
SIDE EFFECTS: The most common adverse effects of tamsulosin are anemia (decreased red blood cells), decreased white blood cells, nausea, vomiting, abnormal taste, increased triglycerides, and weakness. Low blood pressure, dizziness or fainting, headache, abdominal pain, weight loss, muscle pain, abnormal ejaculation, upper respiratory tract infections, and rash also may occur. Orthostatic hypotension (low blood pressure when rising from sitting or lying down position), priapism (prolonged erection), and an eye problem called intraoperative floppy iris syndrome (IFIS) have been observed during tamsulosin treatment.
Reference: FDA Prescribing Information
Last Editorial Review: 3/12/2012
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