tamoxifen, Soltamox, Nolvadex (Discontinued)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Pink Ribbon for Breast Cancer Awareness Month

PREPARATIONS: Tablets: 10 and 20 mg. Solution: 10 mg/5 ml

DRUG INTERACTIONS:

  • Tamoxifen increases the blood thinning effect of warfarin (Coumadin) and reduces blood levels of letrozole (Femara) and anastrozole (Arimidex).
  • Phenobarbital and rifampin may reduce blood levels of tamoxifen by increasing the breakdown of tamoxifen.

PREGNANCY AND BREASTFEEDING SAFETY:

  • Tamoxifen should not be used during pregnancy because it can harm the fetus.
  • It is not known whether tamoxifen is excreted in breast milk. Tamoxifen causes a reduction in milk production. Women taking tamoxifen should not breastfeeding.

STORAGE: Tamoxifen should be stored in a dry place at 15 C - 30 C (59 F - 86 F).

DOSING:

  • The dose for metastatic breast cancer treatment, DCIS, and prevention of breast cancer is 10 mg twice daily or 20 mg once daily for 5 years.
  • he dose for stimulation of ovulation is 5-40 mg twice daily for 4 days.
  • Tamoxifen can be taken with food.
Medically Reviewed by a Doctor on 5/24/2016

Quick GuideBreast Cancer Diagnosis and Treatment

Breast Cancer Diagnosis and Treatment
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

See more info: tamoxifen on RxList
RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Cancer Report Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors