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Takayasu disease facts
- Takayasu disease is a chronic inflammation of the large blood vessels that distributes blood from the heart.
- The cause of Takayasu disease is unknown.
- Symptoms of Takayasu disease include painful, cool, or blanched extremities, dizziness, headaches, chest pain, and abdominal pain.
- The diagnosis of Takayasu disease involves detecting abnormal narrowing of the characteristic blood vessels.
- The treatment of Takayasu disease involves suppressing the inflammation in the blood vessels. Surgical procedures can be required.
What is Takayasu disease?
Takayasu disease is a chronic inflammation of the large blood vessels that distribute blood from the heart, including the aorta and its main branches. Inflammation of blood vessels is also called vasculitis. It is most common in women of Asian descent. It usually begins between 10 and 30 years of age.
What causes Takayasu disease?
The cause of Takayasu disease is unknown. The immune system in patients with Takayasu disease seems to be misdirected to cause inflammation of arteries (arteritis). White blood cells called T lymphocytes are part of the inflammation.
What are symptoms of Takayasu disease?
The inflammation of the aorta and its branch arteries can lead to poor blood supply to tissues of the body in patients with Takayasu disease. This can cause painful, cool, or blanched extremities, dizziness, headaches, chest pain, and abdominal pain. Other symptoms can include fatigue, weight loss, and low-grade fever.