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February 10, 2012
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tacrine - oral, Cognex (cont.)

PRECAUTIONS: Before taking tacrine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: history of liver problems caused by tacrine.Before using this drug, tell your doctor your medical history, including: breathing problems (e.g., asthma, chronic obstructive pulmonary disease-COPD), heart problems (e.g., abnormal heart rhythm), liver disease, seizures, stomach/intestinal disease (e.g., ulcers, bleeding), trouble urinating.This drug may cause loss of coordination. Do not drive, use machinery, or do any activity that requires good coordination until you are sure you can perform such activities safely. Limit alcoholic beverages.Before having surgery, tell your doctor or dentist that you are using this medication.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anticholinergic medications (e.g., benztropine, diphenhydramine), aspirin (high doses, such as those used for arthritis), cholinergic drugs (e.g., bethanechol), drugs affecting liver enzymes that remove tacrine from your body (e.g., cimetidine, fluvoxamine), nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen), succinylcholine, theophylline.Smoking tobacco decreases blood levels of this medication (hepatic enzyme induction). Tell your doctor if you smoke or if you have recently stopped smoking.Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) which, if taken together with tacrine, may increase your risk for stomach/intestinal bleeding. Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day), should be continued. Consult your doctor or pharmacist for more details.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



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