Swine Flu
(Swine Influenza A [H1N1] Virus)

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Swine flu (H1N1 influenza virus) facts

  • Swine flu (swine influenza) is a respiratory disease caused by viruses (influenza viruses) that infect the respiratory tract of pigs and result in nasal secretions, a barking cough, decreased appetite, and listless behavior.
  • Swine flu viruses may mutate (change) so that they are easily transmissible among humans.
  • The 2009 swine flu outbreak is due to infection with the so-called H1N1 virus and was first observed in Mexico.
  • Symptoms of swine flu in humans are similar to most influenza infections: fever (100 F or greater), cough, nasal secretions, fatigue, and headache.
  • Two antiviral agents, zanamivir (Relenza) and oseltamivir (Tamiflu), have been reported to help prevent or reduce the effects of swine flu if taken within 48 hours of the onset of symptoms.

What is swine flu (novel H1N1 influenza A swine flu)?

Swine flu (swine influenza) is a respiratory disease caused by viruses (influenza viruses) that infect the respiratory tract of pigs, resulting in nasal secretions, a barking cough, decreased appetite, and listless behavior. Swine flu produces most of the same symptoms in pigs as human flu produces in people. Swine flu can last about one to two weeks in pigs that survive. Swine influenza virus was first isolated from pigs in 1930 in the U.S. and has been recognized by pork producers and veterinarians to cause infections in pigs worldwide. In a number of instances, people have developed the swine flu infection when they are closely associated with pigs (for example, farmers, pork processors), and likewise, pig populations have occasionally been infected with the human flu infection. In most instances, the cross-species infections (swine virus to man; human flu virus to pigs) have remained in local areas and have not caused national or worldwide infections in either pigs or humans. Unfortunately, this cross-species situation with influenza viruses has had the potential to change. Investigators think the 2009 swine flu strain, first seen in Mexico, should be termed novel H1N1 flu since it is mainly found infecting people and exhibits two main surface antigens, H1 (hemagglutinin type 1) and N1 (neuraminidase type1). Recent investigations show the eight RNA strands from novel H1N1 flu have one strand derived from human flu strains, two from avian (bird) strains, and five from swine strains. Swine flu is transmitted from person to person by inhalation or ingestion of droplets containing virus from people sneezing or coughing; it is not transmitted by eating cooked pork products.

Reviewed by Melissa Conrad Stöppler, MD on 4/10/2012


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What to Do if You Think You Have H1N1 Swine Flu Virus

Medical Author: Melissa Conrad Stöppler, MD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

If you've got fever, cough, or one of the other symptoms of the flu, you may be wondering if you have contracted the H1N1 swine flu virus. The reality is that it isn't possible to know unless specialized testing is ordered, and for uncomplicated cases of the flu in non-hospitalized patients, routine testing for the H1N1 virus is not being carried out.

Experts recommend that people who suspect that they have H1N1 infection stay home and avoid contact with other people. The only time you should leave home is to access medical care if needed. That said, it is important to remember that the vast majority of flu cases (even H1N1 cases) produce only a mild illness for which doctor's visits and/or antiviral drugs are not necessary. So, the presence of cough and fever in an individual who is not at high risk for complications (see below) and who does not have warning signs of a medical emergency should not be a reason to visit an ER. The emergency department should be used for the treatment of people who are very sick or who have life-threatening emergencies (listed below). If you're in doubt, a call to your health-care practitioner can help you decide whether or not you need to access medical care.

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