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Sweet Annie should not be used alone for malaria since it may only inactivate the parasites that cause malaria, not actually kill them. The amount of artemisinin in sweet Annie might be too small to kill all the parasites that cause malaria, but large enough to make these parasites resistant to further treatment with more powerful malaria drugs that also contain artemisinin.
Many researchers are investigating new ways to increase the amount of artemisinin in sweet Annie.
vomiting. It might also cause an allergic reaction in some people including a rash and cough.
There has been one report of liver damage in a person who took doses of sweet Annie that were too large. But liver damage has not been reported in people taking typical doses.
Not enough is known about the safety of applying sweet Annie directly to the skin.
Special Precautions & Warnings:Pregnancy and breast-feeding: Sweet Annie is LIKELY UNSAFE when taken by mouth during pregnancy. Animal studies show that drugs made in the laboratory from artemisinin, a chemical found in sweet Annie, can cause death of the fetus or birth defects when used early in the pregnancy. The safety of using sweet Annie during the last 6 months of pregnancy is not known. Nevertheless, the World Health Organization considers drugs made in the laboratory from artemisinin acceptable to use during the last six months of pregnancy, if no other malaria treatment is available.
The safety of using sweet Annie during breast-feeding is not known. Stay on the safe side and avoid use.
Allergy to ragweed and related plants: Sweet Annie may cause an allergic reaction in people who are sensitive to the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking sweet Annie.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.