sumatriptan, Imitrex, Alsuma, Imitrex STATdose System, Sumavel DosePro (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Combining sumatriptan with sibutramine (Meridia), selective serotonin reuptake inhibitors or SSRIs, including fluoxetine (Prozac), citalopram (Celexa), paroxetine (Paxil), and sertraline (Zoloft) or serotonin and norepinephrine reuptake inhibitors, including venlafaxine (Effexor), duloxetine (Cymbalta), and desvenlafaxine (Pristiq) may increase the concentration of serotonin in the brain, causing increased serotonin-related side effects.

Administering sumatriptan within 24 hours of treatment with an ergot-containing medication (dihydroergotamine [Migranal], ergotamine [Methergine]) is contraindicated because such combinations increase the likelihood of vasospasms.

PREGNANCY: Safe use in pregnancy has not been established.

NURSING MOTHERS: Sumatriptan is excreted in breast milk. Infant exposure may be reduced by avoiding breast feeding for 12 hours after administration of sumatriptan.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information


Medically Reviewed by a Doctor on 1/21/2015


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