sumatriptan, Imitrex, Alsuma, Imitrex STATdose System, Sumavel DosePro (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIBED FOR: All formulations of sumatriptan are used for acute treatment of migraine headaches with or without an aura in adults. The injectable formulation also is used for treating cluster headaches.

SIDE EFFECTS: Side effects are generally transient. Some common side effects of sumatriptan:

  • pain or tightness in the chest or throat,
  • tingling,
  • flushing,
  • weakness,
  • dizziness,
  • abdominal discomfort,
  • sweating,
  • nasal irritation, and
  • injection site reactions.

Rarely, allergic reactions have been reported, usually in individuals who are highly allergic to multiple allergens. Sumatriptan may elevate blood pressure in individuals with or without a history of high blood pressure. Individuals with uncontrolled high blood pressure should not use sumatriptan.

Othere important, but rare, side effects associated with sumatriptan include:



PREPARATIONS: Tablets: 25, 50, 100 mg. Intranasal Solution: 5, 20 mg. Injection Solution: 4 and 6 mg/0.5 ml

STORAGE: Sumatriptan should be stored between 2 C - 30 C (36 F - 86 F).

DOSING: The recommended oral dose is 25-100 mg and the maximum dose is 200 mg daily. The recommended intranasal dose is 5-20 mg and the maximum dose is 40 mg daily. The recommended injection dose is 4 or 6 mg injected under the skin. The maximum dose is two 6 mg injections separated by 1 hour.

DRUG INTERACTIONS: Monoamine oxidase inhibitors, for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane), may reduce the breakdown of sumatriptan in the liver, leading to increased blood levels and side effects of sumatriptan.

Medically Reviewed by a Doctor on 1/21/2015

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