- A Visual Guide to Migraine Headaches Slideshow
- Headache and Migraine Triggers Slideshow
- Take the Migraines Quiz
- What is sumatriptan, and how does it work (mechanism of action)?
- What brand names are available for sumatriptan?
- Is sumatriptan available as a generic drug?
- Do I need a prescription for sumatriptan?
- What are the side effects of sumatriptan?
- What is the dosage for sumatriptan?
- Which drugs or supplements interact with sumatriptan?
- Is sumatriptan safe to take if I'm pregnant or breastfeeding?
- What else should I know about sumatriptan?
What is the dosage for sumatriptan?
- The recommended oral dose is 25-100 mg and the maximum dose is 200 mg daily.
- The recommended intranasal dose is 5-20 mg and the maximum dose is 40 mg daily.
- The recommended injection dose is 4 or 6 mg injected under the skin. T
- he maximum dose is two 6 mg injections separated by 1 hour.
- The recommended dose for the Zecuity patch is one patch applied to dry intact, non-irritated skin on the upper arm or thigh on a site that is relatively hair free and is without scars, tattoos, abrasions, or other skin conditions.
Which drugs or supplements interact with sumatriptan?
Monoamine oxidase inhibitors or MAOIs, for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane), may reduce the breakdown of sumatriptan in the liver, leading to increased blood levels and side effects of sumatriptan.
Combining sumatriptan with sibutramine (Meridia), selective serotonin reuptake inhibitors or SSRIs, including fluoxetine (Prozac), citalopram (Celexa), paroxetine (Paxil), and sertraline (Zoloft) or serotonin and norepinephrine reuptake inhibitors, including venlafaxine (Effexor), duloxetine (Cymbalta), and desvenlafaxine (Pristiq) may increase the concentration of serotonin in the brain, causing increased serotonin-related side effects.
Administering sumatriptan within 24 hours of treatment with an ergot-containing medication (dihydroergotamine [Migranal], ergotamine [Methergine]) is contraindicated because such combinations increase the likelihood of vasospasms.
Quick GuideMigraine or Headache? Migraine Symptoms, Triggers, Treatment
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