GENERIC NAME: sulindac
BRAND NAME: Clinoril
DRUG CLASS AND MECHANISM: Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating pain, fever, and inflammation. Other NSAIDs include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen) as well as others. They work by reducing the levels of prostaglandins, chemicals that are produced by the body and are responsible for pain, fever, and inflammation. Sulindac blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. Sulindac was approved by the FDA in September 1978.
PRESCRIBED FOR: Sulindac is used for the short and long term treatment of pain and fever. It also is used to treat the pain, fever, and swelling and tenderness of joints caused by the inflammation of rheumatoid arthritis, ankylosing spondylitis, gouty arthritis, osteoarthritis, and acute painful shoulder. It also is used for inflammation of soft tissues such as tendinitis and bursitis.
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