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What are examples of sulfonamides available in the US?
Examples of sulfonamides include:
- sulfamethoxazole/trimethoprim (Bactrim, Bactrim DS, Septra, Septra DS)
- sulfasalazine (Azulfidine, Sulfazine)
- sulfisoxazole (Truxazole)
Many of these drugs are available only in generic forms.
What drugs interact with sulfonamides?name="what_drugs_interact_with_sulfonamides">
What drugs interact with sulfonamides?
Sulfonamides can increase the blood-thinning effects of warfarin (Coumadin), possibly leading to abnormal bleeding.
The increased metabolism (break-down and elimination) of cyclosporine by the liver caused by sulfonamides (reduces the effectiveness of cyclosporine and can add to the kidney damage caused by cyclosporine.
Anemia, due to a reduction in folic acid, can occur in persons receiving sulfonamides in combination with divalproex, valproic acid (Depakote, Depakote ER, Depakene, Depacon, Stavzor), methotrexate (Rheumatrex, Trexall), pyrimethamine, triamterene, or trimetrexate.
Increased blood levels of potassium may occur when sulfamethoxazole/trimethoprim is combined with angiotensin converting enzyme (ACE) inhibitors.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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