sulfinpyrazone (Anturane - discontinued in the US)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
Branded and generic forms of sulfinpyrazone have been discontinued in the US for unknown reasons. The FDA has stated that the discontinuation is not for safety reasons.
GENERIC NAME: sulfinpyrazone (Discontinued in the US)
BRAND NAME: Anturane (Discontinued in the US)
DRUG CLASS AND MECHANISM: Sulfinpyrazone is an oral drug that is used to treat gout. Gout is caused by elevated blood levels of uric acid (hyperuricemia). Sulfinpyrazone works by increasing the excretion of uric acid in the urine thereby lowering the elevated levels of uric acid in the blood that are responsible for gout.
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablets: 100mg; Capsules: 200mg.
STORAGE: Sulfinpyrazone should be stored at room temperature in a sealed container.
PRESCRIBED FOR: Sulfinpyrazone is used to reduce elevated blood uric acid levels in patients with gout in order to prevent recurrent attacks of arthritis. It also can help to dissolve the hard deposits of uric acid crystals (tophi) in patients with the tophaceous form of gout.
DOSING: Sulfinpyrazone should be taken with food, milk or antacids. Patients taking sulfinpyrazone long-term should drink plenty of fluids to minimize the risk of uric acid stones forming in the kidneys.
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