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PRECAUTIONS: Before using sulfamethoxazole with trimethoprim injection, tell your doctor or pharmacist if you are allergic to it; or to sulfa medications; or to sodium metabisulfite; or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain blood disorder (anemia due to folate vitamin deficiency), a certain metabolic disorder (porphyria).Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, severe allergies, asthma, diabetes, other blood disorders, decreased bone marrow function (bone marrow suppression), a certain other metabolic disorder (G6PD deficiency), conditions that put you at risk for folate vitamin deficiency (e.g., chronic alcohol use, anti-seizure medication use, intestinal absorption problems, malnutrition).This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.This medication should not be used in infants younger than 2 months.Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, older adults may be more sensitive to the side effects of this drug, especially skin reactions, blood disorders, easy bleeding/bruising, and a high potassium blood level.Patients with AIDS may be more sensitive to the side effects of the drug, especially skin reactions, fever, and blood disorders.During pregnancy, this medication should be used only when clearly needed. This medication should not be used near the expected delivery date because of possible harm to the unborn baby. Discuss the risks and benefits with your doctor.This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended in infants with these conditions. Consult your doctor before breast-feeding any infant.

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