SULFAMETHOXAZOLE WITH TRIMETHOPRIM- ORAL (cont.)
PRECAUTIONS: Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain blood diseases (anemia due to folate deficiency, porphyria), severe kidney disease, severe liver disease. Before using this medication, tell your doctor or pharmacist your medical history, especially of: alcohol use, anti-seizure medication use, severe allergies, asthma, decreased bone marrow function (bone marrow suppression), diabetes, certain genetic conditions (glucose-6-phosphate dehydrogenase deficiency), certain intestinal conditions (e.g., malabsorption), kidney disease, liver disease. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. Caution is advised when using this drug in the elderly because they may be more sensitive to its side effects, especially skin reactions and blood disorders. This medication should be used only when clearly needed during pregnancy. This medication should not be used near term because of possible harm to the fetus. Discuss the risks and benefits with your doctor. This medication passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: dofetilide, methenamine. If you are currently using any of these medications tell your doctor or pharmacist before starting sulfamethoxazole with trimethoprim. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: certain anti-diabetic medications (e.g., glipizide, glyburide, tolbutamide), "blood thinners" (e.g., warfarin), cyclosporine, digoxin, drugs which can increase potassium levels (e.g., ACE inhibitors such as captopril, lisinopril), hydantoins (e.g., phenytoin), live vaccines, methotrexate, oral PABA, procainamide, pyrimethamine, tricyclic antidepressants, certain "water pills" (thiazide diuretics such as hydrochlorothiazide). This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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