sulfamethoxazole and trimethoprim, Bactrim, Septra (cont.)

SIDE EFFECTS:Common side effects of sulfamethoxazole/trimethoprim are:

Sulfamethoxazole/trimethoprim should be stopped at the first appearance of a skin rash before the rash becomes severe. Serious rashes include Stevens-Johnson syndrome (aching joints and muscles; redness, blistering, and peeling of the skin); toxic epidermal necrolysis (difficulty in swallowing; peeling, redness, loosening, and blistering of the skin).

Sulfamethoxazole/trimethoprim therapy also can cause extensive sunburn, following exposure to sunlight. Patients receiving Sulfamethoxazole/trimethoprim should avoid excessive exposure to sunlight (photosensitivity to drugs) and should wear sunscreen.

Other important side effects include:

Sulfamethoxazole/trimethoprim may form crystals in the urine which may damage the kidney and cause bleeding into the urine. It is important to drink additional liquids during therapy to prevent these side effects.

Medically Reviewed by a Doctor on 1/21/2015

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