sulfamethoxazole, Gantanol, Gantanol DS

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: sulfamethoxazole (discontinued)

DISCONTINUED BRANDS: Gantanol, Gantanol DS

DRUG CLASS AND MECHANISM: Sulfamethoxazole is an anti- bacterial sulfonamide. It prevents the formation of dihydrofolic acid, a compound that bacteria must be able to make in order to survive. Although it was once a very useful antibiotic, it is almost obsolete as a single agent today due to the development of bacterial resistance to its effects. Sulfamethoxazole is now used primarily in combination with trimethoprim, a combination product known as Bactrim or Septra. Sulfamethoxazole was approved by the FDA in 1961. According to the FDA database, all brand and generic formulations of sulfamethoxazole have been discontinued.

PRESCRIBED FOR: Sulfamethoxazole is used for the treatment of malaria (in combination with quinine sulfate and pyrimethamine), conjunctivitis (inflammation of the conjunctiva of the eye) due to chlamydia, toxoplasmosis (in combination with pyrimethamine), and urinary tract infections (UTI).

SIDE EFFECTS: Common side effects of sulfamethoxazole are:

Medically Reviewed by a Doctor on 9/15/2015

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