Carafate (sucralfate)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is Carafate (sucralfate)?

Carafate is a unique oral drug that is used for treating ulcers of the upper gastrointestinal tract.

Is Carafate (sucralfate) available as a generic drug?

Yes

Do I need a prescription for Carafate (sucralfate)?

Yes

What are the uses for Carafate (sucralfate)?

  • Carafate is used for the treatment of peptic ulcer disease and to prevent recurrent ulcers after healing of the ulcer has been achieved.
  • Carafate also has been used to relieve or prevent ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs), but is less effective than misoprostol (Cytotec).
  • Carafate also is used in the treatment of patients with gastroesophageal reflux disease (GERD).
  • Off-label uses are to prevent stress ulcers, which are ulcers associated with high degrees of physical stress (for example, extensive burns, surgery, and overwhelming infection) in hospitalized patients.

What are the side effects of Carafate (sucralfate)?

Carafate is well tolerated. Constipation is the most frequent side effect.

Other side effects include:

What is the dosage for Carafate (sucralfate)?

  • The recommended dose for treatment of active ulcers is 1 gram four times daily for 4-8 weeks.
  • Carafate is administered on an empty stomach, at least one hour prior to meals, for best results.
  • The dose for maintenance (preventing recurrent ulcers) is 1 gram twice daily.
Medically Reviewed by a Doctor on 11/17/2016

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