strontium-89 chloride-intravenous, Metastron (cont.)

SIDE EFFECTS: You may experience a flushing sensation while the medication is being injected. Chills and fever have been reported. If any of these effects continue or worsen, inform your doctor. Tell your doctor immediately if you have any of these very unlikely but serious side effects: bloody urine or stools, difficult urination, unusual bleeding or bruising, red spots on the skin, black or tarry stools. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: kidney problems, bone marrow disease, blood disorders, allergies. Because this medication can lower your body's ability to fight an infection, avoid touching your eyes or inside your nose without first washing your hands. Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports in order to lower the chance of getting cut, bruised or injured. Do not have immunizations/vaccinations without consent of your doctor, and avoid contact with people who have recently received oral polio vaccine. Because this medication releases some radiation and the medication may be present in the blood and urine for about 1 week after an injection, use a normal toilet instead of a urinal (if possible) and flush the toilet twice. Wash hands after using the toilet. Wipe any spilled urine or blood with a tissue and flush it away. Immediately wash any clothes or bed linens stained with urine or blood separately from other laundry. This medication is not recommended for use during pregnancy. Consult your doctor before using this medication. It is likely this medication passes into breast milk. Breast- feeding should be stopped while using this medication.

DRUG INTERACTIONS: Tell your doctor or pharmacist of all prescription and nonprescription medications you may use, especially of: all medicines for cancer. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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