Picture: A woman suffering a severe headache could be a sign of stroke.
Stroke

Stroke

Medical Author:
Medical Editor:
Medical Editor:

Stroke facts

  • Stroke is the sudden death of brain cells due to lack of oxygen.
  • Stroke is caused by the blockage of blood flow or rupture of an artery to or in the brain.
  • Sudden tingling, weakness, or paralysis on one side of the body or difficulty with balance, speaking, swallowing, or vision can be a symptom of a stroke.
  • Any person suspected of having a stroke or TIA should present for emergency care immediately.
  • Clot-busting drugs like tPA can be used to reverse a stroke, but the time frame for their use is very narrow. Patients need to present for care as soon as possible so that tPA therapy can be considered.
  • Surgical treatments are used infrequently under special circumstances.
  • Stroke prevention involves minimizing risk factors, such as controlling high blood pressure, elevated cholesterol, tobacco abuse, and diabetes.

What is a stroke?

Brain cell function requires a constant delivery of oxygen and glucose from the bloodstream. A stroke occurs when blood supply to part of the brain is disrupted, leading to inadequate oxygen supply and causing brain cells to die. Blood flow can be compromised in a variety of ways. Stroke is also referred to as cerebrovascular accident (CVA).

Blockage of an artery

  • Narrowing of the small arteries within the brain can cause a lacunar stroke (lacune means "empty space"). Blockage of a single arteriole can affect a tiny area of brain causing that tissue to die (infarct).
  • Hardening of the arteries (atherosclerosis) leading to the brain. There are four major blood vessels that supply the brain with blood. The anterior circulation of the brain's two cerebral cortices controls most motor activity, sensation, thought, speech, and emotion is supplied by the two carotid arteries. The posterior circulation, which supplies the brainstem and the cerebellum, controlling the automatic parts of brain function and coordination, is supplied by the two vertebrobasilar arteries.

If these main arteries become narrowed as a result of atherosclerosis, plaque or cholesterol debris can break off and float downstream, clogging the blood supply to a part of the brain. As opposed to lacunar strokes, larger parts of the brain can lose blood supply, and this may produce more symptoms, with loss of brain and body function, more than seen with a lacunar stroke.

  • Embolism to the brain from the heart. In some instances a thrombus or blood clot can form within the heart and the potential exists for them to break off and travel (embolize) to the arteries in the brain and cause a stroke. Atrial fibrillation, an irregular heart rhythm, is the most common cause of thrombus formation.

Rupture of an artery (hemorrhage)

  • Cerebral hemorrhage (bleeding within the brain substance). The most common reason to have bleeding within the brain is uncontrolled high blood pressure. Other situations include aneurysms that leak or rupture or arteriovenous malformations (AVM) in which there is an abnormal collection of blood vessels that are fragile and can bleed.
Reviewed by William C. Shiel Jr., MD, FACP, FACR on 4/10/2013


Patient Comments

Viewers share their comments

Stroke - Therapy Question: What therapy did you undergo after your stroke?
Stroke - Symptoms Question: For stroke, what were the symptoms and signs you experienced?
Stroke - Risk Factors Question: Do you have any risk factors for stroke? If so, what are they and what are your concerns?
Stroke - Recovery Question: What has recovery been like after you or a loved one suffered a stroke? Please share your story.
Stroke - Prevention Question: To reduce your risk, what dietary or lifestyle changes have you made to prevent a stroke?

Margaret Thatcher Dies of a Stroke

Medical Author: Benjamin Wedro, MD, FACEP, FAAEM
Medical Editor: Charles Patrick Davis, MD, PhD

To every life, an end must come and for the Iron Lady, Margaret Thatcher, that end came because of stroke. She is not alone. Stroke is the number three cause of death, trailing only heart attack and cancer. Death can come quickly. With sufficient brain damage, whether due to a blocked artery or bleeding, swelling can put pressure on the automatic centers of the brain that control breathing and the heart and death is inevitable. But death can also occur later and much more slowly. The ability to swallow can be lost and the risk of aspirating saliva and food can cause pneumonia or a lung infection. The inability to move easily can cause blood clots that travel to the lung; skin can break down and cause major infection.

Stroke is bad but there is potential salvation if the patient gets to medical care fast enough. The window to make the diagnosis and inject clot busting drugs is measured in minutes and many of those are lost because neither the patient nor the family recognizes the signs of a stroke, or they choose to ignore them, hoping that the symptoms will resolve on their own. With symptoms of a transient ischemic attack (TIA), the body fixes itself. Unfortunately, there is no guarantee that the slurred speech, loss of vision, or weakness will get better.

Get the latest health and medical information delivered direct to your inbox FREE!