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February 10, 2012
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streptozocin - injection, Zanosar

GENERIC NAME: STREPTOZOCIN - INJECTION (strep-toe-ZOE-sin)

BRAND NAME(S): Zanosar

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: This medication may cause serious side effects (e.g., kidney damage, severe nausea/vomiting), which may require your treatment with this medication to be stopped. Tell your doctor promptly if you notice symptoms such as unusually decreased/stopped urination. Before starting treatment with this medication, discuss the risks and benefits with your doctor.

USES: Streptozocin is used to treat cancer of the pancreas and other cancers. It works by slowing or stopping the growth of cancer cells.

HOW TO USE: This medication is given by injection into a vein as directed by your doctor. Dosage is based on your medical condition, body size, and response to treatment.Read and learn all preparation and usage instructions supplied by the manufacturer. Follow all instructions for proper handling and mixing with the correct IV fluids. Before using, check the product visually for particles or discoloration. If either is present, do not use the liquid.If this medication touches your skin, immediately wash the area well with soap and water. If this medication gets in your eye, open the eyelids and flush with water for 15 minutes, then seek immediate medical attention.Learn how to store and discard needles and medical supplies safely. Consult your pharmacist for details.Drink plenty of fluids while using this medication unless otherwise directed by your doctor. Doing so may help decrease the risk of side effects (e.g., kidney problems).

SIDE EFFECTS: See also Warning section.Nausea, vomiting, diarrhea, stomach/abdominal pain, or redness/pain/swelling at the injection site may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If these effects persist or worsen, tell your doctor or pharmacist promptly.Severe nausea, vomiting, and diarrhea may infrequently result in a loss of too much body water (dehydration). Contact your doctor promptly if you notice any symptoms of dehydration such as unusual decreased urination, unusual dry mouth/increased thirst, lack of tears, dizziness/lightheadedness, or pale/wrinkled skin.Many people using this medication have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.Tell your doctor immediately if any of these unlikely but serious side effects occur: unusual bleeding/bruising, signs of infection (e.g., fever, chills, persistent sore throat), symptoms of liver disease (e.g., persistent nausea/vomiting, dark urine, yellowing eyes/skin), mental/mood changes (e.g., confusion, depression), unusual weakness.This medication may infrequently cause low blood sugar levels. Tell your doctor promptly if you notice symptoms of low blood sugar such as nervousness, shakiness, fast heartbeat, sweating, and unusual hunger.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.




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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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streptozocin - injection, Zanosar

What is cancer?

Cancer is the uncontrolled growth of abnormal cells anywhere in a body. The abnormal cells are termed cancer cells, malignant cells, or tumor cells. Many cancers and the abnormal cells that compose the cancer tissue are further identified by the name of the tissue that the abnormal cells originated from (for example, breast cancer, lung cancer, colon cancer). Cancer is not confined to humans; animals and other living organisms can get cancer. Below is a schematic that shows normal cell division and how when a cell is damaged or altered without repair to its system, the cell usually dies. Also shown is what can occur when such damaged or unrepaired cells do not die and become cancer cells and proliferate with uncontrolled growth; a mass of cancer cells develop. Frequently, cancer cells can break away from this original mass of cells, travel through the blood and lymph systems, and lodge in other organs where they can again repeat the ...

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