Still's Disease (cont.)

Medical Editor:
Medical Editor:

Is it possible to prevent Still's disease?

There is no prevention for Still's disease.

What types of specialists treat Still's disease?

Still's disease is treated by primary-care physicians, including pediatricians, internists, general practice, and family practice physicians. Typically, these primary-care doctors work with either pediatric or adult rheumatologists in caring for these patients. Depending on organs affected, other specialists who can be involved in the care of patients with Still's disease include cardiologists, pulmonologists, orthopedic surgeons, physical therapists, and occupational therapists.

What Still's disease research is being done?

A wide variety of research is ongoing related to Still's disease. While intravenous immunoglobulin therapy has been used in adult-onset Still's disease, more studies are needed to confirm these results.

Newer IL-1 blockers may prove to be even more effective in treating Still's disease.

Also, TNF-inhibitors (etanercept [Enbrel] and infliximab [Remicade]) have been used successfully in people who have failed other treatments (much as they are now used in rheumatoid arthritis). The intravenous infusions of infliximab helped decrease the Still's disease signs and symptoms, including fever, arthritis, muscle pains, enlarged spleen, and rash in some studies.

What is the prognosis of Still's disease?

Reader Stories

The fever and other systemic features tend to run their course within several months. The arthritis can be a long-term problem. It usually stays on after the systemic features have gone. The arthritis can then become chronic and persist into adulthood. Persisting arthritis of the wrists, with eventual fusion, is common, especially if not treated aggressively. Newer biologic treatments are likely to be beneficial in stopping the progressive joint damage.

REFERENCES:

Klippel, J.H., et al. Primer on the Rheumatic Diseases. New York: Springer, 2008.

Koopman, William, et al., eds. Clinical Primer of Rheumatology. Philadelphia: Lippincott Williams & Wilkins, 2003.

Ruddy, Shaun, et al., eds. Kelley's Textbook of Rheumatology. Philadelphia: W.B. Saunders Co., 2000.


Medically Reviewed by a Doctor on 12/8/2015


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