Steroid and antibiotic eye drops (Blephamide, Isopto, Pred-G, Tobradex, Zylet) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

SIDE EFFECTS: The most common side effects associated with these agents are:

  • irritation,
  • itching,
  • swelling, and
  • redness of the eye.

Allergic reactions and delayed wound healing may occur. Some agents may increase pressure in the eye and worsen glaucoma. Cataract formation and optic nerve damage also may occur.



PREPARATIONS: Steroid and antibiotic combination eye products are available as ointments or suspensions.

STORAGE: They are usually stored at room temperature.

DOSING: Doses range between 1 to 3 drops of the suspension instilled into the eye every 1 to 6 hours. The dose for an ointment is 1/2 inch 3 to 4 times daily. (Patients should see the instructions for each agent for more detailed information about how to use these agents.)

DRUG INTERACTIONS: These drugs work locally in the eye and very little drug is absorbed into the blood stream. There is a low chance of drug interactions with these agents.

PREGNANCY: There are no adequate studies of use of these drugs during pregnancy.

NURSING MOTHERS: Steroids are secreted in breast-milk when taken as pills or injections. These steroid-containing eye drops and ointments have not been adequately studies in women who are breastfeeding.

Medically reviewed by Omudhome Ogbru, PharmD

REFERENCES: FDA Prescribing Information for Blephamide, Catapred, Isopto, Pred-G, Poly-Pred, Tobradex, Zylet

Medically Reviewed by a Doctor on 4/14/2015

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