GENERIC NAME: Steroid and antibiotic eye drops and ointments
Hydrocortisone/neomycin/polymixin B; loteprednol/tobramycin; prednisolone/gentamycin; prednisolone/sulfacetamide; hydrocortisone /neomycin/bacitracin/ polymyxin B
BRAND NAME: Blephamide, Catapred, Isopto, Pred-G, Poly-Pred, Tobradex, Zylet and many other brands
DISCONTINUED BRANDS: Cetapred, Poly-Pred
DRUG CLASS AND MECHANISM: These eye drops and ointments contain a combination of a steroid and one or more types of antibiotic for treatment of infection and inflammation of the eye. The steroid reduces inflammation while the antibiotic treats or prevents infection which may be the cause of the infection. Examples of steroids that are used in these eye drops are hydrocortisone, loteprednol, prednisolone, and dexamethasone. Examples of antibiotics used in these formulations include tobramycin, neomycin, bacitracin, polymixin B, and gentamycin. These antibiotics have different mechanisms of action and two or three may be combined in one formulation.
PRESCRIBED FOR: Steroid and antibiotic eye drops and ointments generally are used for preventing or treating eye infections and associated inflammation.
SIDE EFFECTS: The most common side effects associated with these agents are:
- swelling, and
- redness of the eye.
GENERIC AVAILABLE: Yes for some
PREPARATIONS: Steroid and antibiotic combination eye products are available as ointments or suspensions.
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