St. John's Wort (Hypericum perforatum) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

St. John's wort should be avoided in patients taking prescription antidepressants due to the risk of serotonin syndrome. Symptoms of serotonin syndrome include agitation, hyperthermia (extreme body temperature), sweating, rapid heartbeat, and neuromuscular disturbances.

Additionally, St. John's wort may interact with other prescription medications. All patients should speak to their doctor or pharmacist before taking St. John's wort.

PREGNANCY: Due to the lack of safety data, St. John's wort is not recommended during pregnancy.

NURSING MOTHERS: Due to the lack of safety data, St. John's wort is not recommended during breastfeeding. It is not known if St. John's wort is excreted into breast milk.

REFERENCE: "Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition." Benzie IFF, Wachtel-Galor S, editors. Boca Raton (FL): CRC Press; 2011.


Medically Reviewed by a Doctor on 10/24/2014


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