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st. john's wort (hypericum perforatum) - oral (cont.)

SIDE EFFECTS: Trouble sleeping, restlessness, upset stomach, dizziness, headache, or numbness/tingling of the hands/feet may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.Tell your doctor immediately if this unlikely but serious side effect occurs: a sunburn-like skin reaction (increased sun sensitivity).Tell your doctor immediately if any of these rare but very serious side effects occur: black/bloody/tarry stools, vomit that looks like coffee grounds, easy bruising/bleeding.This product may rarely cause a very serious condition called serotonin syndrome. The risk increases when this product is used with certain drugs such as "triptans" used to treat migraine headaches (e.g., sumatriptan, eletriptan), certain antidepressants including SSRIs (e.g., citalopram, paroxetine) and SNRIs (e.g., duloxetine, venlafaxine), lithium, tramadol, tryptophan, or a certain drug to treat obesity (sibutramine). See also Drug Interactions section. Before taking this product, tell your doctor if you take any of these medications. Serotonin syndrome may be more likely when you start or increase the dose of any of these medications. Seek immediate medical attention if you develop any of the following symptoms: unusual mental/mood changes (e.g., strange thoughts, unusual excitement, extreme anxiety, confusion), severe dizziness, severe headache, fast heartbeat, unexplained fever, sweating, severe nausea/vomiting/diarrhea, twitching muscles.A very serious allergic reaction to this product is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.



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