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spironolactone - oral, Aldactone (cont.)

PRECAUTIONS: Before taking spironolactone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: no urine output (anuria), severe kidney disease, high blood potassium (hyperkalemia).Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver or kidney problems, untreated mineral imbalance (e.g., low sodium).Before having surgery, tell your doctor or dentist that you are taking this medication.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medication because very serious interactions may occur: eplerenone.If you are currently using the medication listed above, tell your doctor or pharmacist before starting spironolactone.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: corticosteroids (e.g., prednisone), certain hormones (ACTH), digoxin, lithium, mitotane, other diuretics that increase potassium (e.g., amiloride, triamterene).Other medications besides this medication which may increase your potassium levels include cyclosporine, tacrolimus, potassium supplements, ACE inhibitors (e.g., captopril, lisinopril) or ARBs (e.g., losartan, candesartan). Follow your doctor's instructions carefully and continue medications for your condition as directed. Limit foods high in potassium such as bananas, tomatoes, potatoes, low-salt milk, and salt substitutes. Consult your doctor or pharmacist for more details, including diet recommendations. It is important to keep all medical and laboratory appointments so your doctor can monitor your potassium levels regularly.Check the labels on all your medicines (such as cough-and-cold products, diet aids, or NSAIDs such as ibuprofen, naproxen) because they may contain ingredients that could increase your blood pressure or worsen swelling (edema).This medication can affect the results of certain lab tests (e.g., digoxin or cortisol levels). Make sure laboratory personnel and your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



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