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November 25, 2009
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SPIRONOLACTONE-ORAL (cont.)

PRECAUTIONS: Tell your doctor your medical history especially of: kidney or liver disease, urinary problems, diabetes, sodium or potassium imbalances, any allergies. Because this drug changes your fluid balance, you may feel dizzy if you change from a lying to a standing position too rapidly. Avoid this by rising slowly. If this drug makes you dizzy, use caution while engaging in activities that require alertness such as driving or using machinery. Before having surgery, including dental surgery, tell the doctor you take spironolactone. This drug should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk and the manufacturer of this drug recommends that breast-feeding not be undertaken while using it. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all medications you may use (both prescription and nonprescription) especially of: other diuretics ("water pills" such as amiloride or triamterene), lithium, digoxin, potassium supplements, cyclosporine, mitotane, ACE inhibitors (e.g., lisinopril, captopril, enalapril), NSAIDs (e.g., ibuprofen, naproxen). Aspirin may decrease the effects of spironolactone. Many nonprescription products contain aspirin. Consult your pharmacist if you are uncertain your nonprescription medicines contain aspirin. This medication may increase your potassium levels. Consult your doctor or pharmacist before using potassium-containing products (salt substitutes or potassium supplements) or large amounts of potassium-containing foods (e.g., bananas, potatoes). Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include nausea, vomiting, weakness, and lightheadedness.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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