sotalol, Betapace, Betapace AF, Sorine, Sotylize

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.


BRAND NAME: Betapace, Betapace AF, Sorine, Sotylize




  • Sotalol is used to treat abnormal heart rhythms such as ventricular arrhythmias (for example, ventricular tachycardia) that are life threatening and atrial fibrillation. It is not used for less severe abnormal heart rhythms.
  • Sotalol should not be used in patients with bronchial asthma, sinus bradycardia, second and third degree AV block, unless a functioning pacemaker is present.
  • It also should not be used in people with congenital or acquired long QT syndromes, cardiogenic shock, uncontrolled congestive heart failure, and people who are allergic to sotalol.


Common side effects of sotalol include:

  • shortness of breath,
  • dizziness,
  • fatigue,
  • palpitation,
  • nausea,
  • vomiting, and
  • lightheadedness.

Other side effects that may occur include:

  • edema (water retention),
  • headache,
  • sleep disturbances,
  • diarrhea,
  • extremity pain,
  • itching,
  • rash,
  • fainting,
  • anxiety,
  • depression,
  • impotence, and
  • abnormal heart rhythm.

Possible serious side effects of sotalol include:

  • mental confusion,
  • slow heart rate,
  • low blood pressure, and
  • chest pain

Like other antiarrhythmic agents, sotalol can cause new or worsening ventricular arrhythmias (for example, ventricular tachycardia or ventricular fibrillation).

Sotalol may cause or worsen congestive heart failure, and it can block the symptoms of low blood glucose in diabetics.

Medically Reviewed by a Doctor on 1/21/2016

Quick GuideHeart Disease: Symptoms, Signs, and Causes

Heart Disease: Symptoms, Signs, and Causes
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

See more info: sotalol-oral on RxList

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Heart Health Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors