sorbitol (Ora-Sweet SF, PCCA Sweet-SF, PCCA Syrup Vehicle, PCCA-Plus, Numoisyn) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DOSING: The initial dose for use as a laxative in adults is 30-150 mL of an oral 70% solution, or 120 mL of a 25% to 30% rectal enema solution. For transurethral surgical procedures, a continuous wash of 3% to 3.3% solution is used.

DRUG INTERACTIONS: Combining sorbitol with calcium/sodium polystyrene sulfonate should be avoided due to the significant risk of causing death of gut tissue (intestinal necrosis).

PREGNANCY: There are no adequate studies of sorbitol in pregnant women.

NURSING MOTHERS: Sorbitol should be used cautiously by nursing mothers.

SIDE EFFECTS: Sorbitol can cause abdominal discomfort, diarrhea, dry mouth, nausea, and vomiting. It may also cause fluid retention in tissues (edema), dehydration, loss of electrolytes, increased blood sugar, and acidification of blood due to lactate production.

REFERENCE: FDA Sorbitol Prescribing Information


Medically Reviewed by a Doctor on 5/15/2014


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