SIDE EFFECTS: Common side effects of sorbitol are:
- abdominal discomfort,
- dry mouth,
- nausea, and
- fluid retention in tissues (edema),
- loss of electrolytes,
- increased blood sugar, and
- acidification of blood due to lactate production.
- Laxative Syrup: No
- Irrigation: Yes
GENERIC AVAILABLE: Yes
PREPARATIONS: Irrigation Solution 3%, 3.3%; Oral Solution 70%, Oral Suspension, Oral Syrup, Lozenge
STORAGE: Sorbitol should be stored at room temperature, 25 C (77 F). Heating above 66 C (150 F) or freezing should be avoided.
DOSING: The initial dose for use as a laxative in adults is 30-150 mL of an oral 70% solution, or 120 mL of a 25% to 30% rectal enema solution. For transurethral surgical procedures, a continuous wash of 3% to 3.3% solution is used.
DRUG INTERACTIONS: Combining sorbitol with calcium/sodium polystyrene sulfonate should be avoided due to the significant risk of causing death of gut tissue (intestinal necrosis).
PREGNANCY: There are no adequate studies of sorbitol in pregnant women.
NURSING MOTHERS: Sorbitol should be used cautiously by nursing mothers.
Medically reviewed by Eni Williams, PharmD
REFERENCE: FDA Sorbitol Prescribing Information
Quick GuideDigestive Disorders: Constipation Myths and Facts
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