sorbitol (Ora-Sweet SF, PCCA Sweet-SF, PCCA Syrup Vehicle, PCCA-Plus, Numoisyn)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Constipation Myths & Facts

SIDE EFFECTS: Common side effects of sorbitol are:

PRESCRIPTION:

  • Laxative Syrup: No
  • Irrigation: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Irrigation Solution 3%, 3.3%; Oral Solution 70%, Oral Suspension, Oral Syrup, Lozenge

STORAGE: Sorbitol should be stored at room temperature, 25 C (77 F). Heating above 66 C (150 F) or freezing should be avoided.

DOSING: The initial dose for use as a laxative in adults is 30-150 mL of an oral 70% solution, or 120 mL of a 25% to 30% rectal enema solution. For transurethral surgical procedures, a continuous wash of 3% to 3.3% solution is used.

DRUG INTERACTIONS: Combining sorbitol with calcium/sodium polystyrene sulfonate should be avoided due to the significant risk of causing death of gut tissue (intestinal necrosis).

PREGNANCY: There are no adequate studies of sorbitol in pregnant women.

NURSING MOTHERS: Sorbitol should be used cautiously by nursing mothers.

Medically reviewed by Eni Williams, PharmD

REFERENCE: FDA Sorbitol Prescribing Information

Medically Reviewed by a Doctor on 9/15/2015

Quick GuideDigestive Disorders: Constipation Myths and Facts

Digestive Disorders: Constipation Myths and Facts
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