GENERIC NAME: sofosbuvir
BRAND NAME: Sovaldi
GENERIC AVAILABLE: No
SIDE EFFECTS: The most common side effects associated with sofosbuvir treatment are:
Other side effect include:
- Decreased appetite,
- muscle pain,
- flu-like symptoms,
- reduced blood cells,
- severe depression, and
- increases in bilirubin levels.
PREPARATIONS: Tablets: 400 mg
DRUG INTERACTIONS: Rifampin and St. John's wort may reduce blood levels of sofosbuvir by increasing its metabolism (break-down) in the intestine. Therefore, sofosbuvir should not be combined with rifampin or St. John's wort. Other drugs that also may reduce blood levels of sofosbuvir include carbamazepine (Tegretol, Tegretol XR , Equetro, Carbatrol), phenytoin (Dilantin, Dilantin-125), phenobarbital, oxcarbazepine (Tripetal), rifabutin, rifampin, rifapentine, and tipranavir (Aptivus)/ritonavir (Norvir).
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