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- What is sodium polystyrene sulfonate-powder, and how does it work (mechanism of action)?
- What brand names are available for sodium polystyrene sulfonate-powder?
- Is sodium polystyrene sulfonate-powder available as a generic drug?
- Do I need a prescription for sodium polystyrene sulfonate-powder?
- What are the side effects of sodium polystyrene sulfonate-powder?
- What is the dosage for sodium polystyrene sulfonate-powder?
- Which drugs or supplements interact with sodium polystyrene sulfonate-powder?
- Is sodium polystyrene sulfonate-powder safe to take if I'm pregnant or breastfeeding?
- What else should I know about sodium polystyrene sulfonate-powder?
What is the dosage for sodium polystyrene sulfonate-powder?
- Oral dosage Adults: The usual recommended dose is 15 g administered 1 to 4 times per day.
- Oral dosage Pediatrics: The usual recommended dose is 1 g/kg administered by mouth every 6 hours as needed.
- Rectal dosage Adults: The usual recommended dose is 30 to 50 g administered rectally every 1-2 hours initially, followed by repeat doses every 6 hours if needed.
- Rectal dosage Pediatrics: The usual recommended dose is 1 g/kg administered rectally every 6 hours as needed.
Which drugs or supplements interact with sodium polystyrene sulfonate-powder?
Cation-donating antacids or laxatives may reduce the effectiveness of sodium polystyrene sulfonate when given concomitantly. Examples of cation-donating antacids and laxatives include:
- aluminum hydroxide,
- calcium carbonate (Caltrate 600, Os-Cal 500, Tums Extra, Tums Chewy Delight, and Many Others),
- magnesium carbonate,
- magnesium citrate, and
- magnesium hydroxide.
Sodium polystyrene sulfonate should be used cautiously with digoxin (Lanoxin) since sodium polystyrene sulfonate-induced hypokalemia (low blood potassium levels) may increase the risk of cardiac toxicity (heart rhythm abnormalities) associated with digoxin.
Concomitant use of sorbitol (Ora-Blend, Ora-Blend SF, Numoisyn Lozenges, Saliva Substitute) with sodium polystyrene sulfonate may cause colonic necrosis. Therefore, use of this combination treatment is not recommended.
Sodium polystyrene sulfonate may decrease the absorption of thyroxine or levothyroxine (Synthroid). Therefore, the administration of thyroid hormones and sodium polystyrene sulfonate should be separated by at least 4 hours.
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