sodium nitroprusside-injection, Nitropress

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GENERIC NAME: SODIUM NITROPRUSSIDE - INJECTION (nye-troh-PRUSS-ide)

BRAND NAME(S): Nitropress

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

WARNING: This drug can cause very large decreases in blood pressure. Without proper monitoring, serious injury or death could result. Nitroprusside, especially in larger-than-recommended doses, might cause cyanide poisoning. Therefore, do not exceed the maximum nitroprusside IV rate (10 mcg/kg/min), especially if the patient has kidney problems. In fact, the maximum IV rate should not be continued more than 10 minutes. If blood pressure is not properly controlled after 10 minutes at the maximum IV rate, nitroprusside should be stopped. Cyanide accumulation might be avoided by monitoring for acid- base metabolic problems (metabolic acidosis), including tests for blood pH. If signs of acidosis occur, nitroprusside may be stopped. Consult the doctor or pharmacist.

USES: This medication is used for the immediate control of very high blood pressure. Nitroprusside is also used to treat certain heart problems (congestive heart failure) or to control bleeding during surgery.

HOW TO USE: This medication is diluted in liquid and given continuously into a vein (IV infusion). Dosage is based on the patient's condition and response to the drug. Maximum recommended doses should not be given for more than 10 minutes. Follow all instructions for proper mixing and dilution with the correct IV fluids. Consult the pharmacist. The diluted fluid should be protected from light by promptly wrapping it with an opaque sleeve or aluminum foil. This medication should be checked visually for particles or discoloration before use. Do not use the liquid if particles are present or if it is blue, green, red or darker than a faint brown color.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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