GENERIC NAME: SODIUM NITROPRUSSIDE - INJECTION (nye-troh-PRUSS-ide)
BRAND NAME(S): Nitropress
WARNING: This drug can cause very large decreases in blood pressure. Without proper monitoring, serious injury or death could result. Nitroprusside, especially in larger-than-recommended doses, might cause cyanide poisoning. Therefore, do not exceed the maximum nitroprusside IV rate (10 mcg/kg/min), especially if the patient has kidney problems. In fact, the maximum IV rate should not be continued more than 10 minutes. If blood pressure is not properly controlled after 10 minutes at the maximum IV rate, nitroprusside should be stopped. Cyanide accumulation might be avoided by monitoring for acid- base metabolic problems (metabolic acidosis), including tests for blood pH. If signs of acidosis occur, nitroprusside may be stopped. Consult the doctor or pharmacist.
USES: This medication is used for the immediate control of very high blood pressure. Nitroprusside is also used to treat certain heart problems (congestive heart failure) or to control bleeding during surgery.
HOW TO USE: This medication is diluted in liquid and given continuously into a vein (IV infusion). Dosage is based on the patient's condition and response to the drug. Maximum recommended doses should not be given for more than 10 minutes. Follow all instructions for proper mixing and dilution with the correct IV fluids. Consult the pharmacist. The diluted fluid should be protected from light by promptly wrapping it with an opaque sleeve or aluminum foil. This medication should be checked visually for particles or discoloration before use. Do not use the liquid if particles are present or if it is blue, green, red or darker than a faint brown color.
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