sodium chloride solution (intravenous)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

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PREGNANCY: It is not known if sodium chloride can cause harm to unborn baby. However, 0.9% sodium chloride (normal saline or NS) has been administered to pregnant women without any reports of harm. The manufacturer recommends that sodium chloride should only be administered to pregnant women if clearly needed. Sodium chloride is classified as FDA pregnancy risk category C (Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.).

NURSING MOTHERS: It is not known if sodium chloride is excreted into human milk. As 0.9% sodium chloride solution has the same osmotic pressure as that in the serum, risk of adverse effects with its use during breastfeeding is considered minimal. However, sodium chloride bacteriostatic injection should be used cautiously in nursing mothers as the benzyl alcohol preservative found in the solution has been found to cause adverse events in the nursing infant.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 5/12/2015
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