sodium chloride solution (intravenous) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIBED FOR: Intravenous sodium chloride is used to replenish fluids and sodium chloride during periods of dehydration and in medical conditions in which additional fluids are needed. It is also used to maintain blood pressure in the treatment of shock. Intravenous sodium chloride is also used as a delivery vehicle for the administration of compatible injectable medicines and to flush IV lines. Intravenous sodium chloride is used in various other health conditions as well.

SIDE EFFECTS: Side effects associated with use of intravenous sodium chloride include:




  • Sodium chloride diluent for injection: 0.9%
  • Sodium chloride solution for injection: 0.9% prefilled syringe, normal saline flush 0.9% solution, sodium chloride 0.45% solution (1/2 NS), sodium chloride hypertonic 3% solution, sodium chloride hypertonic 5% solution.

STORAGE: Sodium chloride preparations should be stored at room temperature between 59 F to 86 F (15 C to 30 C).

DOSING: Dosing of sodium chloride intravenous solution varies. Total volume of administration depends on many factors including condition being treated, laboratory results, and other patient specific characteristics.

Systemic administration of sodium chloride solution should be done with extreme caution as rapid or overt administration may cause complications such as:

  • fluid overload,
  • pulmonary edema (water in the lungs),
  • cell damage,
  • severe electrolyte abnormalities,
  • brain damage, and
  • intraventricular hemorrhage.


Although use of sodium chloride solution has not been associated with any serious or life threatening drug interactions, unintended increases in sodium and water retention may occur when used with corticosteroids.

Medically Reviewed by a Doctor on 5/12/2015

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.

Back to Medications Index