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- What is sodium chloride solution-intravenous, and how does it work (mechanism of action)?
- What brand names are available for sodium chloride solution-intravenous?
- Is sodium chloride solution-intravenous available as a generic drug?
- Do I need a prescription for sodium chloride solution-intravenous?
- What are the side effects of sodium chloride solution-intravenous?
- What is the dosage for sodium chloride solution-intravenous?
- Which drugs or supplements interact with sodium chloride solution-intravenous?
- Is sodium chloride solution-intravenous safe to take if I'm pregnant or breastfeeding?
- What else should I know about sodium chloride solution-intravenous?
What is the dosage for sodium chloride solution-intravenous?
Dosing of sodium chloride intravenous solution varies. Total volume of administration depends on many factors including condition being treated, laboratory results, and other patient specific characteristics.
Systemic administration of sodium chloride solution should be done with extreme caution as rapid or overt administration may cause complications such as:
- fluid overload,
- pulmonary edema (water in the lungs),
- cell damage,
- severe electrolyte abnormalities,
- brain damage, and
- intraventricular hemorrhage.
Which drugs or supplements interact with sodium chloride solution-intravenous?
Although use of sodium chloride solution has not been associated with any serious or life threatening drug interactions, unintended increases in sodium and water retention may occur when used with corticosteroids.
Use of sodium chloride intravenous solution may increase the renal elimination of lithium (Eskalith, Lithobid). Lithium concentrations and control of symptoms should be monitored frequently in patients receiving IV sodium chloride.
Use of tolvaptan (Samsca) with hypertonic preparations of sodium chloride (3% or 5% solution for injection) is not recommended as rapid correction of hyponatremia (low levels of sodium in the blood) increases the risk of osmotic demyelination (nerve damage).
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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