sodium bicarbonate (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Sodium bicarbonate may decrease blood concentration of amphetamines, atazanavir (Reyataz), bisacodyl (Dulcolax), captopril (Capoten), dabigatran (Pradaxa), itraconazole (Sporanox) and many other drugs.

Acetazolamide (Diamox) may increase the risk of toxicity or adverse effects associated with sodium bicarbonate treatment.

PREGNANCY: Sodium bicarbonate has not been adequately evaluated in pregnant women. Sodium bicarbonate has the potential risk of causing metabolic alkalosis and fluid overload in pregnancy. Therefore, sodium bicarbonate containing antacids are considered unsafe in pregnancy.

NURSING MOTHERS: Sodium bicarbonate enters breast milk. Other antacids such as calcium carbonate or magnesium hydroxide are generally preferred over sodium carbonate due to their wider safety margin.

SIDE EFFECTS: Known side effects include belching, flatulence (gas), stomach pain, and edema (water retention).

REFERENCE: FDA Prescribing Information

Medically Reviewed by a Doctor on 10/13/2014

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