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November 21, 2009
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Sleep Aids And Stimulants (cont.)

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What are non-drug treatments for insomnia?

When you consult a physician about insomnia, he or she may ask to you keep a sleep log for several weeks to monitor your sleep habits. The treatment of insomnia includes not only medications, but often sleep habit and behavioral modifications for optimal long-term results.

Evaluating sleep habits is important in the management of insomnia. In some instances, changing sleep habits may correct the problem without the need for medications. Good sleep habits should include:

  • regular sleep times,

  • a comfortable bed and quiet room at a comfortable, temperature,

  • appropriate lighting,

  • regular exercise but not close to bedtime or late in the evening,

  • a bedroom that is not used for work or other activities not related to sleep,

  • avoidance of stimulants (for example, caffeine, or tobacco), alcohol, and large meals close to bedtime,

  • relaxation techniques such as breathing exercises, and

  • avoidance of naps during the day.

What over-the-counter medicines are there for insomnia?

Self-treatment of insomnia with over-the-counter (OTC) drugs is advisable only for transient or short-term insomnia. OTC sleep aids should only be used for a short period of time in conjunction with changes in sleeping habits. Chronic use of these drugs may result in dependence on them. This creates a situation in which sleep is not possible unless the drug is used. Chronic insomnia should be evaluated by a physician.

Antihistamines

Diphenhydramine (for example, Sominex, Nytol) and doxylamine (for example, Unisom) are antihistamines that are currently marketed as OTC sleep aids. Diphenhydramine is the only agent that is considered to be safe and effective by the Food and Drug Administration. The safety and effectiveness of doxylamine has not been evaluated adequately for FDA approval. Other uses for diphenhydramine include allergy, motion sickness, and cough suppression. Scientists believe that diphenhydramine and doxylamine cause sedation by blocking the action of histamine in the brain, but the exact mechanism of action is not known.

If insomnia is associated with pain, there are numerous products containing a combination of an antihistamine and pain reliever. These combination products should not be used if pain is not present because the added pain reliever is not necessary.

Pregnancy and Lactation: The effects of diphenhydramine and doxylamine on the fetus have not been evaluated adequately. Although the likelihood of an adverse effect on the fetus is low, these drugs probably should be avoided during pregnancy. Both agents may decrease lactation (production of milk). Additionally, these drugs are secreted into the breast milk, which could affect the newborn. Therefore, nursing mothers should also avoid both drugs. Children less than 12 years of age should not use doxylamine because its use in this in age group has not been assessed.

Drug Interactions: Diphenhydramine and doxylamine add to the sedative effects of alcohol and other medications that cause drowsiness.

Side Effects: Drowsiness is the most frequent side effect of both diphenhydramine and doxylamine. Therefore, these agents should not be used in situations (for example, driving) where mental alertness is required. Diphenhydramine and doxylamine also cause constipation, dry mouth, and difficulty urinating. Both drugs may worsen the symptoms of glaucoma, asthma, heart problems, and prostate gland enlargement. People with these conditions should not use OTC sleep aids without consulting a physician.

Both drugs may paradoxically cause excitation, resulting in nervousness and insomnia. This occurs most often in children and the elderly.



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