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February 10, 2012

Sleep Glossary of Terms

The following are health and medical definitions of terms that appear in the Sleep article.

Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer).

Addiction: A chronic relapsing condition characterized by compulsive drug-seeking and abuse and by long-lasting chemical changes in the brain. Addiction is the same irrespective of whether the drug is alcohol, amphetamines, cocaine, heroin, marijuana, or nicotine. Every addictive substance induces pleasant states or relieves distress. Continued use of the addictive substance induces adaptive changes in the brain that lead to tolerance, physical dependence, uncontrollable craving and, all too often, relapse. Dependence is at such a point that stopping is very difficult and causes severe physical and mental reactions from withdrawal. The risk of addiction is in part inherited. Genetic factors, for example, account for about 40% of the risk of alcoholism. The genetic factors predisposing to addiction are not yet fully understood.

Aging: The process of becoming older, a process that is genetically determined and environmentally modulated.
See the entire definition of Aging

Airway: The path air follows to get into and out of the lungs. The mouth and nose are the normal entry and exit ports. Entering air then passes through the back of the throat (pharynx), continues through the voice box (larynx), down the trachea, and finally out the branching tubes known as bronchi.

Airway obstruction: Partial or complete blockage of the breathing tubes to the lungs. Obstruction of the airway can be due to different causes including foreign bodies, allergic reactions, infections, anatomical abnormalities and trauma.
See the entire definition of Airway obstruction

Alzheimer's disease: A progressive neurologic disease of the brain that leads to the irreversible loss of neurons and dementia. The clinical hallmarks of Alzheimer's disease are progressive impairment in memory, judgment, decision making, orientation to physical surroundings, and language. A working diagnosis of Alzheimer disease is usually made on the basis of the neurologic examination. A definitive diagnosis can be made only at autopsy. On a cellular level, Alzheimer's disease is characterized by unusual helical protein filaments in nerve cells (neurons) of the brain. These odd twisted filaments are called neurofibrillary tangles. On a functional level, there is degeneration of the cortical regions, especially the frontal and temporal lobes, of the brain.
See the entire definition of Alzheimer's disease

Ambien: Brand name for the sedative hypnotic drug zolpidem used for sleep. For more information, see: zolpidem.

Amitriptyline: An antidepressant medication. In some patients with depression, abnormal levels of brain chemicals called neurotransmitters may relate to the depression. Amitriptyline elevates mood by raising the level of neurotransmitters in brain tissue. Amitriptyline is also a sedative that is useful for depressed patients with insomnia, restlessness, and nervousness. It is sometimes used to treat fibromyalgia and symptoms related to chronic pain. Brand names are Elavil and Endep. A generic version is available.

Antidepressant: Anything, and especially a drug, used to prevent or treat depression.
See the entire definition of Antidepressant

Antihistamines: Drugs that combat the histamine released during an allergic reaction by blocking the action of the histamine on the tissue. Antihistamines do not stop the formation of histamine nor do they stop the conflict between the IgE and antigen. Therefore, antihistamines do not stop the allergic reaction but protect tissues from some of its effects. Antihistamines frequently cause mouth dryness and sleepiness. Newer "non sedating" antihistamines are generally thought to be somewhat less effective. Antihistamine side effects that very occasionally occur include urine retention in males and fast heart rate.

Anxiety: A feeling of apprehension and fear characterized by physical symptoms such as palpitations, sweating, and feelings of stress. Anxiety disorders are serious medical illnesses that affect approximately 19 million American adults. These disorders fill people's lives with overwhelming anxiety and fear. Unlike the relatively mild, brief anxiety caused by a stressful event such as a business presentation or a first date, anxiety disorders are chronic, relentless, and can grow progressively worse if not treated.
See the entire definition of Anxiety

Apnea: An apnea is a period of time during which breathing stops or is markedly reduced. There are two types of apneas, the more common obstructive sleep apnea and the less common central sleep apnea.
See the entire definition of Apnea

Asthma: A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways. Asthma involves only the bronchial tubes and does not affect the air sacs (alveoli) or the lung tissue (the parenchyma of the lung) itself.
See the entire definition of Asthma

Benzodiazepines: A class of drugs that act as tranquilizers and are commonly used in the treatment of anxiety. Benzodiazepines can cause drowsiness.

Brain: That part of the central nervous system that is located within the cranium (skull). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."

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Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.

Caffeine: A stimulant found naturally in coffee beans, tea leaves, cocoa beans (chocolate) and kola nuts (cola) and added to soft drinks, foods, and medicines. A cup of coffee has 100-250 milligrams of caffeine. Black tea brewed for 4 minutes has 40-100 milligrams. Green tea has one-third as much caffeine as black tea.
See the entire definition of Caffeine

Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
See the entire definition of Cancer

Cataplexy: A debilitating medical condition in which a person suddenly feels weak and collapses at moments of strong emotion such as laughter, anger, fear or surprise. In so collapsing, people with cataplexy may injure themselves.
See the entire definition of Cataplexy

Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
See the entire definition of Chronic

Chronic pain: Pain (an unpleasant sense of discomfort) that persists or progresses over a long period of time. In contrast to acute pain that arises suddenly in response to a specific injury and is usually treatable, chronic pain persists over time and is often resistant to medical treatments.
See the entire definition of Chronic pain

Circadian: Refers to events occurring within a 24-hour period, in the span of a full (24-hour) day, as in a circadian rhythm. Circadian rhythmicity is a fundamental property possessed by all organisms. These rhythms are driven by an internal time-keeping system: a clock. Changes in the external environment, particularly in the light-dark cycle, entrain this biologic clock. Under constant environmental conditions devoid of time cues, rhythms driven by the clock show a period near, but usually not exactly equal to, 24 hours.
See the entire definition of Circadian

Continuous positive airway pressure: See: CPAP.

Contrast: Short for "contrast media." Contrast media are X-ray dyes used to provide contrast, for example, between blood vessels and other tissue.

CPAP: Continuous positive airway pressure. CPAP is an effective treatment for obstructive sleep apnea.
See the entire definition of CPAP

Depression: An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
See the entire definition of Depression

ECG: Abbreviation for electrocardiogram or EKG. The K is from "kardio" (in German).

EEG: Electroencephalogram, e technique for studying the electrical current within the brain. Electrodes are attached to the scalp. Wires attach these electrodes to a machine which records the electrical impulses. The results are either printed out or displayed on a computer screen. Electroencephalogram is abbreviated EEG.
See the entire definition of EEG

Elavil: See: Amitriptyline.

Electrocardiogram: A recording of the electrical activity of the heart. An electrocardiogram is a simple, non-invasive procedure. Electrodes are placed on the skin of the chest and connected in a specific order to a machine that, when turned on, measures electrical activity all overaround the heart. Output is usually in the form of a long scroll of paper displaying a printed graph of activity. Newer models output the data directly to a computer and screen, although a print-out may still be made.
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Electroencephalogram: A study of electrical current within the brain. Electrodes are attached to the scalp. Wires attach these electrodes to a machine which records the electrical impulses. The results are either printed out or displayed on a computer screen. Electroencephalogram is abbreviated EEG.
See the entire definition of Electroencephalogram

Endep: See: Amitriptyline.

Essential: 1. Something that cannot be done without.
2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid.
3. Idiopathic. As in essential hypertension. "Essential" is a hallowed term meaning "We don't know the cause."

Exacerbate: To make worse. For example, smoking may exacerbate systemic lupus erythematosus.

Excessive daytime sleepiness: A neurological disorder in which there is a sudden recurrent uncontrollable compulsion to sleep. Excessive daytime sleepiness is also known as narcolepsy.
See the entire definition of Excessive daytime sleepiness

Gene: The basic biological unit of heredity. A segment of deoxyribonucleic acid (DNA) needed to contribute to a function.
See the entire definition of Gene

Genetic: Having to do with genes and genetic information.

Genetics: The scientific study of heredity. Genetics pertains to humans and all other organisms. So, for example, there is human genetics, mouse genetics, fruitfly genetics, etc.
See the entire definition of Genetics

Hygiene: The science of preventive medicine and the preservation of health. From the name of Hygeia, the daughter of Asklepios, the Greek god of medicine (whose staff with entwined snake is the symbol of medicine). Asklepios (known to the Romans as Aesculapius) had a number of children including not only Hygeia but also Panaceia, the patroness of clinical medicine. Hygeia also followed her father into medicine. As the patroness of health, Hygeia was charged with providing a healthy environment to prevent illness. In Greek, "hygieia" means health.

Hypnagogic: Concerning the drowsiness one commonly feels before sleep, the transitional state preceding sleep, and also the hallucinations that may occur at that time.
See the entire definition of Hypnagogic

Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury. The injury may be accidental or deliberate, as with a needlestick injury. The term "injury" may be synonymous (depending on the context) with a wound or with trauma.

Insomnia: The perception or complaint of inadequate or poor-quality sleep because of one or more of the following: difficulty falling asleep; waking up frequently during the night with difficulty returning to sleep; waking up too early in the morning; or unrefreshing sleep. Insomnia is not defined by the number of hours of sleep a person gets or how long it takes to fall asleep. Individuals vary normally in their need for, and their satisfaction with, sleep. Insomnia may cause problems during the day, such as tiredness, a lack of energy, difficulty concentrating, and irritability.
See the entire definition of Insomnia

Jet lag: A temporary disorder that causes fatigue, insomnia, and other symptoms as a result of rapid air travel across time zones.
See the entire definition of Jet lag

Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."

Leg: In popular usage, the leg extends from the top of the thigh down to the foot. However, in medical terminology, the leg refers to the portion of the lower extremity from the knee to the ankle.
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Limb: The arm or leg.

Medical history: 1. In clinical medicine, the patient's past and present which may contain clues bearing on their health past, present, and future. The medical history, being an account of all medical events and problems a person has experienced, including psychiatric illness, is especially helpful when a differential diagnosis is needed.
2. The history of medicine.

Melatonin: A hormone produced by the pineal gland, melatonin is intimately involved in regulating the sleeping and waking cycles, among other processes. Melatonin supplements are sometimes used by people who have chronic insomnia. Always see your doctor before taking melatonin, as it is not recommended for all patients with sleep problems.

Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."

Muscular: Having to do with the muscles. Also, endowed with above average muscle development. Muscular system refers to all of the muscles of the body collectively.

Myoclonus: A condition of abnormal contraction of muscles or portions of muscles.

Narcolepsy: A neurological disorder marked by a sudden recurrent uncontrollable compulsion to sleep. Narcolepsy is often associated with cataplexy (a sudden loss of muscle tone and paralysis of voluntary muscles associated with a strong emotion), sleep paralysis (immobility of the body that occurs in the transition from sleep to wakefulness), what are called hypnagogic hallucinations (pre-sleep dreams) and automatic behaviors (such as doing something "automatically" and not remembering afterwards how one did it).
See the entire definition of Narcolepsy

Nasal: Having to do with the nose. Nasal drops are intended for the nose, not (for example) the eyes. The word "nasal" came from the Latin "nasus" meaning the nose or snout.

Nicotine: An alkaloid (a nitrogen-containing chemical) made by the tobacco plant or produced synthetically. In the plant kingdom, nicotine is not restricted to tobacco but is widespread. The tobacco plant, Nicotiana tabacum, belongs to the nightshade family, which also includes potatoes, tomatoes, eggplant and red peppers. All contain nicotine. However, the concentration of nicotine in those vegetables is far lower than the level in tobacco. Nicotine has powerful pharmacologic effects (including increased heart rate, heart stroke volume, and oxygen consumption by the heart muscle) as well as powerful psychodynamic effects (such as euphoria, increased alertness, and a sense of relaxation). As is now well known, nicotine is also powerfully addictive. When someone becomes habituated to nicotine and then stops using it, they experience the symptoms of withdrawal, including anxiety, irritability, restlessness, shortened attention span and an intense, sometimes irresistible, craving for nicotine.
See the entire definition of Nicotine

NIH: The National Institutes of Health. The NIH is an important U.S. health agency. It is devoted to medical research. Administratively under the Department of Health and Human Services (HHS), the NIH consists of 20-some separate Institutes and Centers. NIH's program activities are represented by these Institutes and Centers.
See the entire definition of NIH

NREM sleep: NREM (non-rapid eye movement) sleep is dreamless sleep. During NREM, the brain waves on the electroencephalographic (EEG) recording are typically slow and of high voltage, the breathing and heart rate are slow and regular, the blood pressure is low, and the sleeper is relatively still. NREM sleep is divided into 4 stages of increasing depth leading to REM sleep.
See the entire definition of NREM sleep

Obstruction: Blockage of a passageway. See, for example: Airway obstruction; Intestinal obstruction.

Obstructive sleep apnea (OSA): Sleep apnea is a breathing disorder characterized by brief interruptions of breathing during sleep. It owes its name to a Greek word, apnea, meaning "want of breath."
See the entire definition of Obstructive sleep apnea

Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis. There is always an onset to a disease but never to the return to good health. The default setting is good health.
See the entire definition of Onset

Oxygen: A colorless, odorless and tasteless gas that makes up about 20% of the air we breathe (and at least half the weight of the entire solid crust of the earth) and which combines with most of the other elements to form oxides. Oxygen is essential to human, animal and plant life.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
See the entire definition of Pain

Paralysis: Loss of voluntary movement (motor function). Paralysis that affects only one muscle or limb is partial paralysis, also known as palsy; paralysis of all muscles is total paralysis, as may occur in cases of botulism.

Physiologic: Something that is normal, neither due to anything pathologic nor significant in terms of causing illness.

Polysomnography: Continuous recording of specific physiologic variables during sleep. Polysomnography typically records brain wave changes (electroencephalogram), eye movements (electrooculogram), muscle tone (electromyogram), respiration, electrocardiogram (EKG), and leg movements.

Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
See the entire definition of Pregnancy

Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

Psychiatric: Pertaining to or within the purview of psychiatry, the medical specialty concerned with the prevention, diagnosis, and treatment of mental illness.
See the entire definition of Psychiatric

REM sleep: REM sleep is the portion of sleep when there are rapid eye movements (REMs).
See the entire definition of REM sleep

Remedy: Something that consistently helps treat or cure a disease. From the Latin "remedium" meaning that which heals again (and again).
See the entire definition of Remedy

Restless leg syndrome: An uncomfortable creeping, crawling, tingling, pulling, twitching, tearing, aching, throbbing, prickling or grabbing sensation in the calves that occurs while sitting or while lying down. Whatever the nature of the sensation, the result is an uncontrollable urge to relieve it by moving the legs.
See the entire definition of Restless leg syndrome

Restless legs: See: Restless leg syndrome.

Sedative: A drug that calms a patient down, easing agitation and permitting sleep. Sedatives generally work by modulating signals within the central nervous system. These sedatives can dangerously depress important signals needed to maintain heart and lung function if they are misused or accidentally combined, as in the case of combining prescription sedatives with alcohol. Most sedatives also have addictive potential. For these reasons, sedatives should be used under supervision, and only as needed.

Seizure: Uncontrolled electrical activity in the brain, which may produce a physical convulsion, minor physical signs, thought disturbances, or a combination of symptoms.
See the entire definition of Seizure

Sleep: The body's rest cycle.
See the entire definition of Sleep

Sleep apnea: The temporary stoppage of breathing during sleep, often resulting in daytime sleepiness. Apnea is a Greek word that means "want of breath."
See the entire definition of Sleep apnea back to top

Sleep disorders: Any disorder that affects, disrupts, or involves sleep. The most common sleep disorder is probably snoring, although it is usually not medically significant. Insomnia, sleep apnea, restless leg syndrome, and sleepwalking are also sleep disorders. Most large medical centers have diagnostic and treatment facilities dedicated to sleep disorders.
See the entire definition of Sleep disorders

Sleep hygiene: A series of practices and non-medical treatments for insomnia. Sleep hygiene includes simple steps that may improve initiation and maintenance of sleep, such as maintaining a regular sleep schedule, making the bedroom an inviting place to sleep, avoiding alcohol or smoking prior to going to bed, and exercising regularly (but not in the 4-5 hours prior to bedtime).

Sleep paralysis: A frightening form of paralysis that occurs when a person suddenly finds himself or herself unable to move for a few minutes, most often upon falling asleep or waking up. Sleep paralysis is due to an irregularity in passing between the stages of sleep and wakefulness.
See the entire definition of Sleep paralysis

Sleepwalking: Purposeful moving, usually but not always including walking, while in a deep stage of sleep. Sleepwalking occurs most frequently in children, particularly boys. Sedatives tend to exacerbate rather than cure sleepwalking. The best measures are preventative: ensure that the sleepwalker is in a safe room for walking, and cannot accidentally fall through an open window or down stairs. Some types of sleepwalking are related to seizure disorders , bipolar disorder, or other neurological conditions, but most cases are transitory and due to unknown causes. Also called somnambulism.

Snoring: A rough rattling noise made on inspiration during sleep by vibration of the soft palate (the back of the roof of the mouth) and the uvula (the prominent structure dangling down at the back of the mouth).
See the entire definition of Snoring

Sonata: Sonorous brand name for the sedative hypnotic drug generically known as zaleplon, used for sleep. For more pharmaceutical information, see: zaleplon.

Stage: As regards cancer, the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging.

Stroke: The sudden death of some brain cells due to a lack of oxygen when the blood flow to the brain is impaired by blockage or rupture of an artery to the brain. A stroke is also called a cerebrovascular accident or, for short, a CVA.
See the entire definition of Stroke

Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.

Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
See the entire definition of Syndrome

Therapy: The treatment of disease.
See the entire definition of Therapy

Tired: A feeling of a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a sense of weariness and fatigue.
See the entire definition of Tired

Tobacco: A South American herb, formally known as Nicotiana tabacum, whose leaves contain 2-8% nicotine and serve as the source of smoking and smokeless tobacco.
See the entire definition of Tobacco

Topical: Pertaining to a particular surface area. A topical agent is applied to a certain area of the skin and is intended to affect only the area to which it is applied. Whether its effects are indeed limited to that area depends upon whether the agent stays where it is put or is absorbed into the blood stream.

Trimester: The nine months of pregnancy is traditionally divided into three trimesters: distinct periods of roughly three months in which different phases of fetal development take place.
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Voluntary: Done in accordance with the conscious will of the individual. The opposite of involuntary.
See the entire definition of Voluntary

Zaleplon: Brand name: Sonata. A sedative hypnotic drug in a class closely related the benzodiazepines, affecting the central nervous system, used as a sleep drug. For more information, see: zaleplon.

Zolpidem: Brand name: Ambien. A sedative hypnotic drug in a class closely related the benzodiazepines, affecting the central nervous system, used as a sleep drug. For more information, see: zolpidem.

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      • Eye strain is a symptom caused by looking at something for a long time. Symptoms and signs include redness, light sensitivity, headaches, and blurred vision. Symptoms may be treated by closing the eyes and taking a break from the visual task.
    • Teen Drug Abuse
      • Drugs commonly abused by teens include tobacco products, marijuana, cold medications, inhalants, depressants, stimulants, narcotics, hallucinogens, PCP, ketamine, Ecstasy, and anabolic steroids. Some of the symptoms and warning signs of teen drug abuse include reddened whites of eyes, paranoia, sleepiness, excessive happiness, seizures, memory loss, increased appetite, discolored fingertips, lips or teeth, and irritability. Treatment of drug addiction may involve a combination of medication, individual, and familial interventions.
    • Stress Management Techniques
      • Stress may be considered as any physical, chemical, or emotional factor that causes bodily or mental unrest and that may be a factor in disease causation. An important goal for those under stress is the management of stress in our lives. Elimination of stress is unrealistic, since stress is a part of normal life. We can however, learn to manage stress through techniques such as exercise, relaxation, meditation, time management, and support systems so that we have control over our stress and its effects on our physical and mental health.
    • Insomnia Treatment (Sleep Aids and Stimulants)
      • Insomnia is difficulty in falling or staying asleep, the absence of restful sleep, or poor quality of sleep. Insomnia is a symptom and not a disease. The most common causes of insomnia are medications, psychological conditions, environmental changes and stressful events. Treatments may include non-drug treatments, over-the-counter medicines, and/or prescription medications.
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What is a depressive disorder?

Depressive disorders have been with mankind since the beginning of recorded history. In the Bible, King David, as well as Job, suffered from this affliction. Hippocrates referred to depression as melancholia, which literally means black bile. Black bile, along with blood, phlegm, and yellow bile were the four humors (fluids) that described the basic medical physiology theory of that time. Depression, also referred to as clinical depression, has been portrayed in literature and the arts for hundreds of years, but what do we mean today when we refer to a depressive disorder? In the 19th century, depression was seen as an inherited weakness of temperament. In the first half of the 20th century, Freud linked the development of depression to guilt and conflict. John Cheever, the author and a modern sufferer of depressive disorder, wrote of conflict and experiences with his parents as influencing his development of depression.

In the 19...

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