GENERIC NAME: SIROLIMUS TABLETS - ORAL (sir-oh-LEE-muss)
BRAND NAME(S): Rapamune
Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert
WARNING: This medication may make you more likely to develop an infection or certain types of cancer (e.g., lymphoma, skin cancer). Notify your doctor immediately if you develop any signs of an infection such as fever, chills, sore throat, white patches in your mouth, or a change in vaginal discharge. Also, notify your doctor immediately if you have unusual lumps, swollen glands, unusual swelling, or unexplained weight loss. When sirolimus has been used in liver transplants, an infrequent but potentially fatal liver problem has occurred (hepatic artery thrombosis). Use of this medication to prevent rejection of liver transplants is not recommended. Notify your doctor immediately if you develop: dark urine, stomach pain, yellowing eyes or skin, extreme fatigue or nausea. When sirolimus has been used in lung transplants, an infrequent but potentially fatal lung problem has occurred (bronchial anastomotic dehiscence). Use of this medication to prevent rejection of lung transplants is not recommended. Notify your doctor immediately if you develop: difficulty breathing.
USES: This medication is used to prevent the rejection of transplanted organs (e.g., kidney transplant).
HOW TO USE: Take this medication by mouth usually once daily, exactly as prescribed by your doctor. The dosage is based on your medical condition and response to therapy. This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals (e.g., every 24 hours) and take this drug consistently either with or without food. Other medications (e.g., antibiotics, immunosuppressants) may be prescribed to help prevent infection in your body and to help prevent rejection of the transplanted organ. Take these additional medications exactly as prescribed by your doctor. If you are prescribed cyclosporine along with sirolimus, take this medication four hours after your cyclosporine dose. Consult your pharmacist for more information.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
- Kidney Failure - Learn about kidney failure, in which the body has fluid retention, risen blood pressure, toxin build up and lack of red blood cells. Symptoms include fatigue, nausea, and apetite loss.
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