simethicone, Phazyme, Mi-Acid, Gas Relief, Mytab Gas, Gas-X, Gas-X Extra Strength

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

GENERIC NAME: simethicone

BRAND NAME: Phazyme, Mi-Acid, Gas Relief, Mytab Gas, Gas-X, Gas-X Extra Strength, Gas-X Ultra Strength

DISCONTINUED BRANDS: Equalizer Gas Relief, Gas Free, Gas Free Extra Strength, Flatulex, Mylicon, and Mylanta Gas



USES: Simethicone relieves abdominal pain due to excessive gas in the digestive tract. It also is given to patients undergoing upper abdominal ultrasound imaging.

SIDE EFFECTS: Common side effects may include:

PREPARATIONS: Liquid drops: 40 mg per 0.6 ml. Chewable tablets: 40, 80 and 125 mg. Capsules: 125 and 180 mg.

DRUG INTERACTIONS: There are no known drug interactions with simethicone.

PREGNANCY AND BREASTFEEDING SAFETY: Safety during pregnancy has not been adequately evaluated. Simethicone is generally considered safe during pregnancy because it does not cross the placenta.

Simethicone is considered safe during lactation because it is not absorbed into the body and infants are often treated with simethicone.

STORAGE: Preparations should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

DOSING: The recommended dose for relieving gas is 40-125 mg 4 times daily after meals and at bedtime. The drops can be mixed with water, infant formula or other liquids for use in small children.

DRUG CLASS AND MECHANISM: Simethicone is an anti-gas (anti-flatulence) medication. It acts in the stomach and intestines to change the surface tension of gas bubbles, enabling their breakdown and the formation of larger bubbles. In this way it is believed that gas can be eliminated more easily by belching or passing flatus. Simethicone was approved by the FDA in 1952.

Medically reviewed by Eni Williams, PharmD, PhD


FDA Prescribing Information.

Black R, Hill A. Over the counter medications in pregnancy. Am Fam Physician. 2003 Jun 15;67(12):2517-2524.

Medically Reviewed by a Doctor on 8/1/2016

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Digestive Disorders: Common Misconceptions
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