simeprevir, Olysio

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GENERIC NAME: simeprevir

BRAND NAME: Olysio

DRUG CLASS AND MECHANISM: Simeprevir is an oral, direct-acting an-tiviral agent used for treating infections with the hepatitis C virus (HCV). Boceprevir (Victrelis), telaprevir (Incivek), and sofosbuvir (Sovaldi) are other direct-acting drugs for treating HCV. Simeprevir blocks the effect of pro-teases which are enzymes that HCV needs for making new viruses, leading to reduced numbers of HCV in the body. Simeprevir is effective for treating people infected with HCV genotype 1, including those with liver disease. The FDA approved simeprevir in November 2013.

PRESCRIBED FOR: Simeprevir is used in combination with ribavirin (Rebetol, Copegus) and peginterferon to treat infections with HCV.

SIDE EFFECTS: The most common side effects associated with simeprevir treatment are:

Medically Reviewed by a Doctor on 1/12/2015



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