silver sulfadiazine (Silvadene, SSD, SSD AF, Thermazene)

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GENERIC NAME: silver sulfadiazine

BRAND NAME: Silvadene, SSD, SSD AF, Thermazene

DRUG CLASS AND MECHANISM: Silver sulfadiazine is a topical (applied to the skin) antimicrobial agent used to treat and prevent skin infections caused by second or third degree burns.

Silver sulfadiazine kills bacteria by damaging the bacterial cell membrane. Silver sulfadiazine has activity against a broad spectrum of gram-positive and gram-negative bacteria including Pseudomonas aeruginosa, Xanthomonas maltophilia, Enterobacter species, Klebsiella species, Escherichia coli, Serratia species, Proteus mirabilis, Morganella morganii, Providencia rettgeri, Proteus vulgaris, Providencia species, Citrobacter species, Acinetobacter calcoaceticus, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus species, Candida albicans, Corynebacterium diphtheriae, and Clostridium perfringens. Additionally, silver sulfadiazine has demonstrated activity against yeast.

Medically Reviewed by a Doctor on 2/4/2015

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