silver sulfadiazine (Silvadene, SSD, SSD AF, Thermazene)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

What brand names are available for silver sulfadiazine-topical?

Silvadene, SSD, SSD AF, Thermazene

Is silver sulfadiazine-topical available as a generic drug?


Do I need a prescription for silver sulfadiazine-topical?


What are the uses for silver sulfadiazine-topical?

What are the side effects of silver sulfadiazine-topical?

  • Since silver sulfadiazine is applied to the surface of the skin, it rarely affects other areas of the body or causes long term side effects.
  • Most of the side effects reported with use are short lived and limited to the areas being treated.
  • Use of silver sulfadiazine may cause the treated area(s) to be more sensitive to sunlight (photosensitive or sun sensitive). To avoid sunburn, patients must take caution in protecting the affected area(s) from prolonged sun exposure.
  • Other rare skin reactions reported with silver sulfadiazine use include
    • skin necrosis (skin death),
    • redness,
    • burning sensation of the treated area(s),
    • itching,
    • rash, and
    • brownish-gray skin discoloration.
  • Rarely, a drop in white blood cells has been reported with silver sulfadiazine therapy. Drop in white blood counts peak within 2-4 days of starting treatment and usually return to normal limits following 2-3 days of onset.
  • Patients are advised to speak to their pharmacist or doctor for a complete list of side effects, including those caused by sulfonamides.
Medically Reviewed by a Doctor on 9/28/2016

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