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February 10, 2012

Severe Acute Respiratory Syndrome (SARS) (cont.)

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What causes SARS? How is SARS transmitted?

SARS is caused by a virus referred to as "SARS-CoV" from the coronavirus genus; SARS-CoV means severe acute respiratory syndrome-associated coronavirus. The genus coronavirus includes viruses that infect animals and a few that cause the common cold in humans. However, the SARS-CoV virus is different than other coronaviruses and had never been identified before 2002. This was not entirely surprising because there are many types of coronaviruses and they are known to mutate easily.

Although scientists are not certain, it has been suggested that the SARS virus originated in wild bats and then spread to palm civets or similar mammals. The virus then gradually mutated until it could infect humans. There was ample opportunity for the virus to come into contact with humans. Bats serve as a food source in parts of Asia, and their feces are sometimes used in folk medicines. Civets are catlike mammals that live in the tropics of Africa and Asia and produce musk from their scent glands, which is used in perfumes. Civets are also hunted for meat in some parts of the world.

SARS-CoV is spread from person to person through respiratory secretions. SARS often affected people caring for a sick individual and spread readily through health-care facilities until infection-control measures were established. During the outbreak, one in about every 20 infected people was a health-care worker who cared for a patient with SARS.

What are risk factors for SARS?

SARS-CoV can infect a person regardless of their health status or age group. However, it was clear that some people were at increased risk during the 2002 outbreak. This included people over the age of 50 (some reported mortality rates of about 50%), pregnant women, and those with underlying diabetes, heart disease, or liver disease. A major risk factor is simply a close association with any person infected with SARS-CoV since the virus is easily spread through droplets spewed into the air.



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