GENERIC NAME: sertraline
BRAND NAME: Zoloft
GENERIC AVAILABLE: Yes
USES: Sertraline is used for treating depression, obsessive-compulsive disorder (OCD), panic disorder, and post-traumatic stress disorder (PTSD). Sertraline also is used for treating social anxiety disorder and premenstrual dysphoric disorder (PMDD).
WARNING: As demonstrated in short-term studies, antidepressants increased the risk of suicidal thinking and behavior (suicidality) in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of sertraline or any other antidepressant in a child or adolescent must balance this risk with the clinical need for the antidepressant. Patients who are started on therapy should be closely observed for clinical worsening, suicidal thoughts, or unusual changes in behavior.
SIDE EFFECTS: The most common side effects of sertraline are
- skin rash,
- upset stomach,
- loss of appetite,
- abnormal ejaculation,
- decreased interest in sexual activity,
- dry mouth,
- increase in sweating, known as diaphoresis, and
- weight loss.
If sertraline is discontinued abruptly, some patients experience side effects such as:
- abdominal cramps,
- diminished appetite,
- flu-like symptoms,
- sweating ,
- sleep disturbances, and
- memory impairment.
A gradual dose reduction of sertraline is recommended when therapy is discontinued.
Quick GuideDepression Hurts: Physical Symptoms of Depression
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.