The following are health and medical definitions of terms that appear in the Sepsis article. Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Abortion: In medicine, an abortion is the premature exit of the products of conception (the fetus, fetal membranes, and placenta) from the uterus. It is the loss of a pregnancy and does not refer to why that pregnancy was lost.
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Amputation: Removal of part or all of a body part enclosed by skin. For example, removal of part of a finger or an entire finger would be termed an amputation. Removal of an appendix, on the other hand, would not be termed amputation. A person who has undergone an amputation is called an amputee.
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Analysis: A psychology term for processes used to gain understanding of complex emotional or behavioral issues.
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Bacteremia: The presence of live bacteria in the bloodstream. Bacteremia is analogous to viremia (the presence of a virus in the blood) and parasitemia (the presence of a parasite in the blood). Bacteremia, viremia and parasitemia are all forms of sepsis (bloodstream infection). The term "bacteremia" was compounded from "bacteria" and "-emia" (in the blood). Also called bacillemia.
Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Bacterial: Of or pertaining to bacteria. For example, a bacterial lung infection.
Blood culture: A test designed to detect if microorganisms such as bacteria and fungi are present in blood. A sample of blood obtained using sterile technique is placed in a culture media and incubated in a controlled environment for 1 to 7 days. If microorganisms grow, they can be identified as to type and tested against different antibiotics for proper treatment of the infection. Because microorganisms may only be intermittently present in blood, a series of 3 blood cultures is usually done before the result is considered negative.
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Blood poisoning: The medical term is "septicemia." No matter which of these two terms-blood poisoning or septicemia-you prefer, what is meant is the same thing, namely a "general (systemic) disease that is due to the presence and the persistence of germs (pathogenic microorganisms) or their toxins in the bloodstream." The "germs" can be bacteria (in bacteremia) or any other microscopic agent of infection capable of causing disease in humans. Another term that is very closely related to "blood poisoning" and "septicemia" is "sepsis." "Sepsis" also refers to the presence and persistence of germs or their toxins in the blood but those germs or toxins do not need to be in the blood. They may be in other tissues of the body. Blood poisoning/septicemia and sepsis are often serious. They can sometimes be life threatening diseases calling for urgent and comprehensive care.
Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".
Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
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Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.
Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Carbon dioxide: A gas which is the byproduct of cellular metabolism and which collects in the tissues, is cleared from the tissues by the blood within the veins, is carried by the hemoglobin in the red blood cells, and removed from the body via the lungs in the exhaled air. Abbreviated CO2.
Catheter: A thin, flexible tube . For example, a catheter placed in a vein provides a pathway for giving drugs, nutrients, fluids, or blood products. Samples of blood can also be withdrawn through the catheter.
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
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Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
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Cough: A rapid expulsion of air from the lungs typically in order to clear the lung airways of fluids, mucus, or material. Also called tussis.
Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Dialysis: The process of cleansing the blood by passing it through a special machine. Dialysis is necessary when the kidneys are not able to filter the blood. Dialysis allows patients with kidney failure a chance to live productive lives. There are two types of dialysis: hemodialysis and peritoneal dialysis. Each type of dialysis has advantages and disadvantages. Patients can often choose the type of long term dialysis that best matches their needs.
Drain: A device for removing fluid from a cavity or wound. A drain is typically a tube or wick. As a verb, to allow fluid to be released from a confined area.
Dysfunction: Difficult function or abnormal function.
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Dysuria: Painful or difficult urination. This includes burning on urination. Dysuria is most commonly due to bacterial infection of the urinary tract causing inflammation of the bladder ( cystitis ) or kidney ( pyelonephritis ).
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Enterococcus: Bacteria normally found in the feces of people and many animals. Two types of enterococci -- Enterococcus faecalis and Enterococcus faecium --occasionally cause human disease, most commonly urinary tract infections and wound infections. Other infections, including those of the blood stream (bacteraemia), heart valves (endocarditis) and the brain ( meningitis ) can occur in severely ill patients in hospitals. Enterococci also often colonize open wounds and skin ulcers.
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Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Fungal: Pertaining to a fungus. For example, a fungal skin infection.
Fungi: Plural of fungus.
Gastrointestinal: Adjective referring collectively to the stomach and small and large intestines.
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Gastrointestinal tract: The tube that extends from the mouth to the anus in which the movement of muscles and release of hormones and enzymes digest food. The gastrointestinal tract starts with the mouth and proceeds to the esophagus, stomach, duodenum, small intestine, large intestine (colon), rectum and, finally, the anus. Also called the alimentary canal, digestive tract and, perhaps most often in conversation, the GI tract.
Gram-negative: Gram-negative bacteria lose the crystal violet stain (and take the color of the red counterstain) in Gram's method of staining. This is characteristic of bacteria that have a cell wall composed of a thin layer of a particular substance (called peptidoglycan).
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Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
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Heart rate: The number of heart beats per unit time, usually per minute. The heart rate is based on the number of contractions of the ventricles (the lower chambers of the heart). The heart rate may be too fast ( tachycardia ) or too slow ( bradycardia ). The pulse is bulge of an artery from the wave of blood coursing through the blood vessel as a result of the heart beat. The pulse is often taken at the wrist to estimate the heart rate.
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Hemorrhagic: Pertaining to bleeding or the abnormal flow of blood.
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Hygiene: The science of preventive medicine and the preservation of health. From the name of Hygeia, the daughter of Asklepios, the Greek god of medicine (whose staff with entwined snake is the symbol of medicine). Asklepios (known to the Romans as Aesculapius) had a number of children including not only Hygeia but also Panaceia, the patroness of clinical medicine. Hygeia also followed her father into medicine. As the patroness of health, Hygeia was charged with providing a healthy environment to prevent illness. In Greek, "hygieia" means health.
Hypotension: Any blood pressure that is below the normal expected for an individual in a given environment. Hypotension is the opposite of hypertension (abnormally high blood pressure).
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Hypothermia: Abnormally low body temperature. The condition needs treatment at body temperatures of 35C (95 F) or below. And hypothermia becomes life threatening below body temperatures of 32.2 C (90 F).
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ICU: Intensive Care Unit.
Immune: Protected against infection. The Latin immunis means free, exempt.
Indicate: In medicine, to make a treatment or procedure advisable because of a particular condition or circumstance. For example, certain medications are indicated for the treatment of hypertension during pregnancy while others are contraindicated.
Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Inflammatory response: A fundamental type of response by the body to disease and injury, a response characterized by the classical signs of "dolor, calor, rubor, and tumor " -- pain , heat (localized warmth), redness, and swelling.
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Intensive care: See critical care.
Intubation: The process of putting a tube into a hollow organ or passageway, often into the airway . The opposite of intubation is extubation.
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Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.
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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
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Limb: The arm or leg.
Lymphangitis: The red streaking and gland (lymph node) swelling in the area of an injury especially on the extremities. It is usually caused by a bacterial infection with Streptococcus. The bacteria enter the body through a cut, scrape, bite or wound of some sort. The bacteria can get into the lymphatic system, which is part of our immune system. The bacterial infection spreads rapidly in the lymph channels (causing the red streaking) and lymph nodes (causing hard swollen "knots" under the skin). If left untreated, the bacteria can spread in the skin around the area, causing cellulitis, and also rapidly spread to the bloodstream, causing sepsis. In the days before antibiotics people referred to lymphangitis as "blood poisoning" due to the infection rapidly causing severe illness and sometimes death.
Lymphatic: 1. One of the lymphatics, vessel that convey the lymph fluid. 2. Pertaining to the lymph, lymphoid tissue, or lymphocytes. 3. Lacking energy. Sluggish.
From the Latin lympha (water or water goddess), from the Greek nymphe (nymph).
Maternal: 1. Pertaining to the mother as, for example, the maternal mortality rate. 2. Related through the mother as, for example, the maternal grandparents. 3. Inherited from the mother as, for example, the maternal X chromosome.
Meninges: The three membranes that cover the brain and spinal cord (singular: meninx).
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Meningitis: Inflammation of the meninges, usually due to a bacterial infection but sometimes from viral, protozoan, or other causes (in some cases the cause cannot be determined).
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Mortality: A fatal outcome or, in one word, death. The word "mortality" is derived from "mortal" which came from the Latin "mors" (death). The opposite of mortality is, of course, immortality. Mortality is also quite distinct from morbidity (illness).
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Mortality rate: A death rate . There are a number of different types of mortality rates as, for examples, the following: - The fetal mortality rate : The ratio of fetal deaths to the sum of the births (the live births + the fetal deaths) in that year.
- The infant mortality rate : The number of children dying under a year of age divided by the number of live births that year.
- The maternal mortality rate : The number of maternal deaths related to childbearing divided by the number of live births (or by the number of live births + fetal deaths) in that year.
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Neisseria: Group of bacteria that includes the cause of gonorrhea.
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Neonatal: Pertaining to the newborn period which, by convention, is the first four weeks after birth.
Neonatal sepsis: A serious blood bacterial infection in an infant less than 4 weeks of age. Babies with sepsis may be listless, overly sleepy, floppy, weak, and very pale.
Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye, ear, heart, lungs, and liver.
Organ failure: The failure of an essential system in the body. Multiple organ failure is the failure of two or more systems, such as the cardiovascular, and renal systems, and is a common consequence of sepsis (the presence of bacteria in the bloods) and of shock (very low blood pressure).
Pediatric: Pertaining to children.
Poisoning: Taking a substance that is injurious to health or can cause death. Poisoning is still a major hazard to children, despite child-resistant (and sometimes adult-resistant) packaging and dose-limits per container.
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Postpartum: In the period just after delivery, as with postpartum depression. Postpartum refers to the mother and postnatal to the baby. From the Latin post, after + partum, birth.
Prognosis: 1. The expected course of a disease .
2. The patient's chance of recovery.
The prognosis predicts the outcome of a disease and therefore the future for the patient . His prognosis is grim, for example, while hers is good.
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Pulse: The rhythmic contraction and expansion of an artery due to the surge of blood from the beat of the heart. The pulse is most often measured by feeling the arteries of the wrist. There is also a pulse, although far weaker, in veins.
Pus: A thick whitish-yellow fluid which results from the accumulation of white blood cells (WBCs), liquified tissue and cellular debris. Pus is commonly a site of infection or foreign material in the body.
Reproductive system: In women, the organs that are directly involved in producing eggs and in conceiving and carrying babies. In men, the organs directly involved in creating, storing, and delivering sperm to fertilize an egg.
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Respiratory: Having to do with respiration, the exchange of oxygen and carbon dioxide. From the Latin re- (again) + spirare (to breathe) = to breathe again.
Respiratory rate: The number of breaths per minute or, more formally, the number of movements indicative of inspiration and expiration per unit time. In practice, the respiratory rate is usually determined by counting the number of times the chest rises or falls per minute. By whatever means, the aim is to determine if the respirations are normal, abnormally fast (tachypnea), abnormally slow (bradypnea), or nonexistent (apnea).
Sepsis: Commonly called a "blood stream infection." The presence of bacteria (bacteremia) or other infectious organisms or their toxins in the blood (septicemia) or in other tissue of the body. Sepsis may be associated with clinical symptoms of systemic (bodywide) illness, such as fever , chills, malaise (generally feeling "rotten"), low blood pressure , and mental status changes. Sepsis can be a serious situation, a life threatening disease calling for urgent and comprehensive care.
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Septic: Infected, or denoting infection. For example, septic shock is shock caused by infection.
Septicemia: Systemic (bodywide) illness with toxicity due to invasion of the bloodstream by virulent bacteria coming from a local seat of infection. The symptoms of chills, fever and exhaustion are caused by the bacteria and substances they produce. The disorder is treated with massive doses of antibiotics. Also known as blood poisoning.
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Shock: In medicine, shock is a critical condition brought on by a sudden drop in blood flow through the body. There is failure of the circulatory system to maintain adequate blood flow. This sharply curtails the delivery of oxygen and nutrients to vital organs. It also compromises the kidney and so curtails the removal of wastes from the body. Shock can be due to a number of different mechanisms including not enough blood volume (hypovolemic shock) and not enough output of blood by the heart (cardiogenic shock). The signs and symptoms of shock include low blood pressure (hypotension), overbreathing (hyperventilation), a weak rapid pulse, cold clammy grayish-bluish (cyanotic) skin, decreased urine flow (oliguria), and mental changes (a sense of great anxiety and foreboding, confusion and, sometimes, combativeness).
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Stage: As regards cancer , the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging .
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Staphylococcus: A group of bacteria that cause a multitude of diseases. Under a microscope, Staphylococcus bacteria are round and bunched together. They can cause illness directly by infection, or indirectly through products they make, such as the toxins responsible for food poisoning and toxic shock syndrome. The best known member of the Staphylococcus family is Staphylococcus aureus. Staphylococcus are the main culprit in hospital-acquired infections, and cause thousands of deaths every year.
Streptococcus: A group of bacteria, familiarly known as strep, that cause a multitude of diseases. The name comes from the Greek strepto- meaning twisted + kokkos meaning berry, and that is exactly what strep look like under the microscope, like a twisted bunch of little round berries. Illness caused by strep includes strep throat, strep pneumonia, scarlet fever, rheumatic fever (and rheumatic heart valve damage), glomerulonephritis, the skin disorder erysipelas, and PANDAS.
Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Systemic: Affecting the entire body. A systemic disease such as diabetes can affect the whole body. Systemic chemotherapy employs drugs that travel through the bloodstream and reach and affect cells all over the body.
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Tachycardia: A rapid heart rate, usually defined as greater than 100 beats per minute. The tachycardias include sinus tachycardia , paroxysmal atrial tachycardia (PAT), and ventricular tachycardia .
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Tattoo: The permanent insertion of ink or other pigments below the skin using a sharp instrument. Humans have done tattooing for cosmetic and ritual purposes since at least the Neolithic era. In the Western world, tattooing has historically served as a brand of criminality, a sign of shame (like "The Scarlet Letter" of Nathaniel Hawthorne), a tradition dating back at least to the biblical mark of Cain. Note along these lines also the branding of slaves, the tattooing of prisoners of war in ancient Athens, and the marking of the foreheads of French prisoners in the 18th and 19th centuries with letters signifying their punishment. In the Middle Ages tattooing was done of Christian pilgrims in Jerusalem, the tattoo symbolizing the "stigmata of the Lord Jesus." In the Renaissance tattooing was done of astrologic signs to invoke their magical powers.
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Therapeutic: Relating to therapeutics , that part of medicine concerned specifically with the treatment of disease . The therapeutic dose of a drug is the amount needed to treat a disease.
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Therapy: The treatment of disease .
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Thermometer: A device used to measure the temperature of gaseous, liquid or solid matter or of a chemical reaction such as fire. Temperature measurement is important to a wide range of activities, including industry, scientific research, and health care. In health care, thermometers are used to measure the temperature of the human body. They include the following types:
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Urinary: Having to do with the kidneys, ureters, and bladder. The urinary system represents the functional and anatomic aspects of the kidneys, ureters, and bladder.
Urinary tract: The organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.
Urinary tract infection: Infection of the kidney, ureter, bladder, or urethra. Not everyone with a UTI has symptoms. Common symptoms include a frequent urge to urinate and a painful, burning when urinating. More females than males have UTIs. Underlying conditions that impair the normal urinary flow can lead to complicated UTIs.
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Urine: Liquid waste. The urine is a clear, transparent fluid. It normally has an amber color. The average amount of urine excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous (watery) solution of salt (sodium chloride) and substances called urea and uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter. Abnormally, it may contain sugar (in diabetes), albumen (a protein) (as in some forms of kidney disease), bile pigments (as in jaundice), or abnormal quantities of one or another of its normal components.
Vaccines: Microbial preparations of killed or modified microorganisms that can stimulate an immune response in the body to prevent future infection with similar microorganisms. These preparations are usually delivered by injection.
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White blood cell: One of the cells the body makes to help fight infections. There are several types of white blood cells ( leukocytes ). The two most common types are the lymphocytes and neutrophils (also called polymorphonuclear leukocytes, PMNs, or "polys").
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White blood cell count (leukocyte count): The number of white blood cells (WBCs) in the blood. The WBC is usually measured as part of the CBC ( complete blood count ). White blood cells are the infection-fighting cells in the blood and are distinct from the red (oxygen-carrying) blood cells known as erythrocytes. There are different types of white blood cells, including neutrophils (polymorphonuclear leukocytes ; PMNs), band cells (slightly immature neutrophils), T-type lymphocytes (T cells), B-type lymphocytes (B cells), monocytes, eosinophils, and basophils. All the types of white blood cells are reflected in the white blood cell count. The normal range for the white blood cell count varies between laboratories but is usually between 4,300 and 10,800 cells per cubic millimeter of blood. This can also be referred to as the leukocyte count and can be expressed in international units as 4.3 - 10.8 x 109 cells per liter.
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- vancomycin-oral, Vancocin - Consumer information about the medication VANCOMYCIN - ORAL (Vancocin), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug VANCOMYCIN - ORAL.
- Dialysis - Dialysis is a procedure that performs many of the normal duties of the kidneys, like filtering waste products from the blood, when the kidneys no longer work adequately. There are two types of dialysis: hemodialysis and peritoneal dialysis.
- Urinary Tract Infection (UTI In Adults) - Learn about urinary tract infection causes, symptoms, signs, diagnosis and treatment of UTIs in men and women. Antibiotics may be used to treat recurrent bladder infections.
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