Vaginal Pain and Vulvodynia - Medications

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What medications or other medical treatments have helped your vaginal pain (vulvodynia)?

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Medications and other medical therapies for vaginal pain and vulvodynia

Some of the medications that have been useful include:

  • Topical estrogen creams
  • Topical or local anesthetics
  • Tricyclic antidepressants
  • Anticonvulsants (anti-seizure medications are sometimes useful in managing chronic pain)

Other medical therapies for women with severe vulvodynia include:

  • Injections of interferon or nerve blocks, in which medications are injected to reduce signaling from nerves in the affected areas
  • Biofeedback training and pelvic floor exercises have been helpful for some women.
  • Surgical removal of affected tissue can be of benefit in women with vulvodynia due to vulvar vestibulitis syndrome, a particular type of vulvodynia that is located at the area of the hymenal ring.
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See what others are saying

Comment from: Cravitts, 45-54 Female (Patient) Published: March 19

I suffered through the burning pain after a hysterectomy, and couldn"t sit on hard surfaces without wanting to scream. Finally after a few visits to an obstetrician/gynecologist, she diagnosed vulvodynia and prescribed amitriptyline. My dosage is 75mg, 50mg helped most of the time but still had painful flare-ups.

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Comment from: kestrel, 55-64 Female (Patient) Published: December 13

I don't think anyone has suggested amitriptyline. This antidepressant can be prescribed in low doses for vulvodynia and other pain. The 10 mg I take each evening has alleviate my vulvodynia pain. Higher dosages can also be prescribed but as this medication can make you feel drowsy I will stick to the 10mg dose for now.

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