Genetic Disease - Symptoms

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Multifactorial inheritance

Multifactorial inheritance, also called complex or polygenic inheritance. Multifactorial inheritance disorders are caused by a combination of environmental factors and mutations in multiple genes. For example, different genes that influencebreast cancer susceptibility have been found on chromosomes 6, 11, 13, 14, 15, 17, and 22. Some common chronic diseases are multifactorial disorders.

Examples of multifactorial inheritance include:

  • heart disease,
  • high blood pressure,
  • Alzheimer's disease,
  • arthritis,
  • diabetes,
  • cancer, and
  • obesity.

Multifactorial inheritance also is associated with heritable traits such as fingerprint patterns, height, eye color, and skin color.

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Comment from: nithi, 7-12 Male (Caregiver) Published: February 18

My kid's skin is soft and dry and hence easily prone to bleeding even for a scratch. He has no sweat and no tears, has only 4 teeth in the upper jaw and 4 in the lower jaw. There is bleeding in the right nostril when the environment temperature is very hot or when the kid catches cold. He has less hair in the head and eyebrows and no hair in any of the other parts of the body. He is unable to consume hot and spicy food.

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