Liver Disease - Symptoms

Not ready to share? Read other Patient Comments

What were your symptoms associated with liver disease?

Share your story with others:

MedicineNet appreciates your comment. Your comment may be displayed on the site and will always be published anonymously.Patient Comments FAQs

Enter your Comment

Tell us a bit about your background to make your comments more useful to other MedicineNet users. (Optional)

Screen Name: *

Gender of Patient: Male Female

Age Range of Patient:

I am a: Patient Caregiver

* Screen Name will appear next to the published comment. Please do not include your full name or email address.

By submitting your comment, and other materials (collectively referred to as a "Submission") to MedicineNet, you grant MedicineNet permission to use, copy, transmit, publish, display, edit and modify your Submission in connection with its Web site. MedicineNet will not pay you for your Submission. You represent that you have all rights necessary for MedicineNet to use your Submission as set forth above.

Please keep these guidelines in mind when writing your comment:

  • Please make sure you address the question asked.
  • Due to the overwhelming number of comments received, not all comments will be published.
  • When selecting comments to publish, our staff will choose those that are educational and complement the topic. Please try to stay on topic.
  • Your comment may be edited. We would typically edit comments to make them clearer and more readable. We will remove personal information such as last names, email and web addresses, and other potentially harmful information.
  • We will not notify you if your comment has been published. We suggest that you check back on the topic article regularly.
  • We do not provide medical or healthcare advice, treatment, or diagnosis.

Thank you for participating!

I have read and agree to abide by the MedicineNet Terms and Conditions and the MedicineNet Privacy Policy (required).

To prevent our systems from spam, please complete the following prior to submitting your comment.

Please select the black square:

What are the symptoms of liver disease?

Classic symptoms of liver disease include:

  • nausea,
  • vomiting,
  • right upper quadrant abdominal pain, and
  • jaundice (a yellow discoloration of the skin due to elevated bilirubin concentrations in the bloodstream).

Fatigue, weakness and weight loss may also be occur.

However, since there are a variety of liver diseases, the symptoms tend to be specific for that illness until late-stage liver disease and liver failure occurs.

Examples of liver disease symptoms due to certain conditions or diseases include:

  • A person with gallstones may experience right upper abdominal pain and vomiting after eating a greasy (fatty) meal. If the gallbladder becomes infected, fever may occur.
  • Gilbert's disease has no symptoms, and in an incidental finding on a blood test where the bilirubin level is mildly elevated.
  • Individuals with cirrhosis will develop progressive symptoms as the liver fails. Some symptoms are directly related to the inability of the liver to metabolize the body's waste products. Others reflect the failure of the liver to manufacture proteins required for body function and may affect blood clotting function, secondary sex characteristics and brain function. Symptoms of cirrhosis of the liver include:
    • easy bruising may occur due to decreased production of clotting factors;
    • bile salts can deposit in the skin causing itching;
    • gynecomastia or enlarged breasts in men may occur because of an imbalance in sex hormones; specifically an increase in estradiol;
    • impotence (erectile dysfunction, ED), poor sex drive and shrinking testicles are due to decrease in function of sex hormones;
    • confusion and lethargy may occur if ammonia levels rise in the blood stream (ammonia is a waste product formed from protein metabolism and requires normal liver cells to remove it), ascites (fluid accumulation within the abdominal cavity) occurs because of decreased protein production; and
    • muscle wasting may occur because of reduced protein production.

Additionally, there is increased pressure within the cirrhotic liver affecting blood flow through the liver. Increased pressure in the portal vein causes blood flow to the liver to slow down and blood vessels to swell. Swollen veins (varices) form around the stomach and esophagus and are at risk for bleeding.

Return to Liver Disease

See what others are saying

Comment from: Alley, 19-24 Male (Caregiver) Published: February 20

Liver treatment surgeons across the globe point out that in almost 50 percent of cases, liver diseases do not show any symptoms. However, the more prominent symptoms include those of jaundice or the eyes and skin turning yellowish due to accumulation of bilirubin in the white areas. In addition, dark urine, clay-colored stool, gastrointestinal tract bleeding and retention of fluids in the belly area are some notable symptoms of liver diseases.

Was this comment helpful?Yes
Comment from: Isla, 55-64 Female (Patient) Published: April 11

I have constant upper right abdominal pain through to my back and under my right shoulder blade. My liver function tests show there are problems. I often have yellowing of the whites of my eyes, I rarely ever drink alcohol and when I do it"s half a glass of wine. However I just seem to be shunted from one consultant to another for a proper diagnosis but am not getting any help. I am constantly exhausted, I can easily sleep most of the weekend from Friday night to Monday morning just getting up for a few hours to wash and to eat. If I don"t do this I can"t cope with my full time job. I am depressed and so tired all the time.

Was this comment helpful?Yes


Get the latest health and medical information delivered direct to your inbox!