Chronic Fatigue Syndrome - Symptoms

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What are systemic exertion intolerance disease or chronic fatigue syndrome symptoms and signs?

The symptoms and signs of CFS/SEID are complex but specific. The patient must have severe chronic fatigue of six months or longer duration with other known medical conditions excluded by clinical diagnosis. In addition, the patients have four or more of the following symptoms that either occurred at the same time or after the severe chronic fatigue. The symptoms are substantial impairment in short-term memory or concentration; sore throat; tender lymph nodes; muscle pain; multi-joint pain without swelling or redness; headaches of a new type, pattern, or severity; unrefreshing sleep; and post-exertion malaise lasting more than 24 hours. Patients may often have additional symptoms such as double vision, mild fevers, earaches, diarrhea, and many other symptoms, but they do not fit into the criteria that are considered to be part of the definition of CFS.

The following are five main symptoms that the new IOM considers key for SEID or CFS:

  • Reduction or impairment in ability to carry out normal daily activities, accompanied by profound fatigue
  • Post-exertional malaise (worsening of symptoms after physical, cognitive, or emotional effort)
  • Unrefreshing sleep
  • Cognitive impairment
  • Orthostatic intolerance (symptoms that worsen when a person stands upright and improve when the person lies back down)
Return to Chronic Fatigue Syndrome (CFS or SEID)

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