Enlarged Spleen - Treatment

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What is the treatment for an enlarged spleen?

Because splenomegaly is due to an underlying illness, treatment will depend upon the primary cause. In some situations, removal of the spleen (splenectomy) may be part of the treatment. For example, in hereditary spherocytosis, misshapen red blood cells are filtered from the blood stream causing anemia and an enlarged spleen. Splenectomy limits the number of red blood cells destroyed and helps treat the disease.

Return to Enlarged Spleen (Splenomegaly)

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Comment from: Loulabell, 65-74 Female (Patient) Published: April 11

My enlarged spleen is the result of an underlying disease: myeloproliferative disease (MPD). My bone marrow is producing immature cells which get filtered by the spleen, causing it to work overtime and enlarge. Treatment for the MPD has been hydroxyurea 500 mg. I have been on it for 2 plus years. Seems to have improved RBC, WBC, platelet and LDH levels, but has not reduced the size of the spleen.

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Comment from: DanielMc, 35-44 Male (Patient) Published: January 08

My spleen enlargement was due to eosinophilia caused by a food allergy. This was discovered after seeing my general physician, an oncologist, an IDS (infectious disease specialist), and my allergist and running full blood panel test, bone marrow, as well as x-ray, ultrasound, CT, and MRI. After all that all tests came back negative. They could not figure out why my eosinophil count was about 57 percent. My allergist put me on the Paleo diet and within 1.5 weeks, I noticed a huge difference and was feeling much better. A follow up appointment showed my count to be back in the normal 6 to 8 percent range. When I test foods not on the diet (particularly those with gluten) I start to experience the symptoms again.

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