Enlarged Spleen - Treatment

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What is the treatment for an enlarged spleen?

Because splenomegaly is due to another underlying illness, treatment will depend upon the primary cause. In some situations, removal of the spleen (splenectomy) may be part of the treatment. For example, in hereditary spherocytosis, misshapen red blood cells are filtered from the blood stream causing anemia and an enlarged spleen. Splenectomy limits the number of red blood cells destroyed and helps treat the disease.

Return to Enlarged Spleen (Splenomegaly)

See what others are saying

Comment from: Billy, 45-54 Male (Patient) Published: April 07

My enlarged spleen was the result of an enlarged liver, resulting from a high fat diet and high cholesterol/tri lipids. I was ordered to lose massive weight to recover.

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Comment from: Loulabell, 65-74 Female (Patient) Published: April 11

My enlarged spleen is the result of an underlying disease: myeloproliferative disease (MPD). My bone marrow is producing immature cells which get filtered by the spleen, causing it to work overtime and enlarge. Treatment for the MPD has been hydroxyurea 500 mg. I have been on it for 2 plus years. Seems to have improved RBC, WBC, platelet and LDH levels, but has not reduced the size of the spleen.

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